Results 101 to 110 of about 2,138,397 (299)

Chilean Export Performance: the Rol of Intensive and Extensive Margins [PDF]

open access: yes
The paper presents a detailed description of the evolution of non-copper exports in the 1990-2007 period and decomposes its evolution in terms of the intensive and extensive margins. I document a significant export diversification in terms of markets and
Matías Berthelon
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Specific speed and overall dimensions in calculation and selection of transverse fans

open access: yesTraktory i sel hozmashiny, 2016
When calculating, designing and selecting the fans, along with the similarity theory and dimensional analysis, the criteria of specific speed and overall dimensions are used, which allow to study a great number of aerodynamic configurations and characteristics of highly efficient fan prototypes and at the same time to choose the configuration which ...
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Multivariate Time Series Similarity Searching

open access: yesThe Scientific World Journal, 2014
Multivariate time series (MTS) datasets are very common in various financial, multimedia, and hydrological fields. In this paper, a dimension-combination method is proposed to search similar sequences for MTS.
Jimin Wang   +4 more
doaj   +1 more source

The perceived value in ecotourism related to satisfaction and loyalty: A study from Costa Rica [PDF]

open access: yesGeographica Pannonica, 2020
Ecotourism allows activities in contact with nature in protected natural areas to contribute to environmental care. This study seeks to establish the dimensions of perceived value in ecotourism and analyze its relationship with satisfaction and loyalty ...
Carvache-Franco Mauricio   +4 more
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Quality of Life of Children with Cancer: Do Caregivers Perceive

open access: yesJournal of Health Science and Medical Research (JHSMR), 2013
The aims of this study were to determine the quality of life of children with cancer and to compare their perceived quality of life with those of their caregivers.
Busakorn Punthmatharith   +2 more
doaj  

SENSITIVITAS ETIS DAN PERTIMBANGAN MORAL MAHASISWA AKUNTANSI TERHADAP DILEMA BISNIS

open access: yesJurnal Akuntansi, 2019
and perceived societal pressure) to the ethical sensitivity and moral judgments of accounting students and to prove the influence of the dimension of moral intensity to the moral judgments through ethical sensitivity.
Kiki Apriyana, Lisa Martiah Nila Puspita
doaj   +1 more source

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