Results 101 to 110 of about 1,877,507 (306)

Is progression-free survival a more relevant endpoint than overall survival in first-line HR+/HER2− metastatic breast cancer?

, 2018
Anna Forsythe,1 David Chandiwana,2 Janina Barth,3 Marroon Thabane,4 Johan Baeck,5 Anastasiya Shor,1 Gabriel Tremblay6 1Health Technology Assessment Evidence, Purple Squirrel Economics, New York, NY, USA; 2Global Value and Access, Novartis Pharmaceutical ...
Thabane M, Forsythe A, Tremblay G, Shor A, Baeck J, Chandiwana D, Barth J   +6 more
core  

Overall survival.

, 2019
The overall survival rate at 5 years was 94.7%.
Takashi Nakano (253277), Hidemasa Kawamura (2620510), Takuya Kaminuma (6400784), Hiro Sato (545155), Nobuteru Kubo (2620519), Masahiro Onishi (6400790), Masahiko Okamoto (2298643), Nobuaki Ohtake (3193428), Tetsuo Sekihara (6400793), Yosuke Takakusagi (6400781), Tatsuji Mizukami (6400787)   +10 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Nomograms for Predicting Overall and Cancer-Specific Survival Among Second Primary Endometrial Cancer in Primary Colorectal Carcinoma Patients [PDF]

Linli Liu Department of Gynecology, Fuzhou First General Hospital, Affiliated to Fujian Medical University, Taijiang District, Fuzhou, Fujian, People’s Republic of ChinaCorrespondence: Linli Liu, Department of Gynecology, Fuzhou First General Hospital ...
Liu L
core  

Upregulation of the EMT marker vimentin is associated with poor clinical outcome in acute myeloid leukemia

Journal of Translational Medicine, 2018
Background Vimentin (VIM) is a type III intermediate filament that maintains cell integrity, and is involved in cell migration, motility and adhesion.
Sharon Wu, Yang Du, John Beckford, Houda Alachkar   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Sites of metastasis and overall survival in esophageal cancer: a population-based study

, 2017
San-Gang Wu,1,* Wen-Wen Zhang,2,* Zhen-Yu He,2 Jia-Yuan Sun,2 Yong-Xiong Chen,3 Ling Guo4 1Department of Radiation Oncology, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Xiamen, 2Department of Radiation Oncology, Sun Yat ...
Zhang WW, Guo L, Sun JY, He ZY, Wu SG, Chen YX   +5 more
core  

Age as a Predictor of Overall Survival in Colorectal Cancer

Diagnostics
Background: The diagnosis of colorectal cancer (CRC) at early ages has become a challenging trend for oncology due to high rates of mortality worldwide. The correlation of clinical features with young-age prognosis in CRC remains unclear. Therefore, we aimed to describe the clinicopathological features and their impact on the overall survival of young ...
Berenice Carbajal-López, Jossimar Coronel-Hernández, Marytere Herrera, Erika Ruiz-Garcia, Sayako M. Miyagui-Adame, Consuelo Diaz-Romero, Eduardo Osiris Madrigal-Santillán, Priscila Morales Esponda-Mendoza, Carlos Pérez-Plasencia, Germán Calderillo-Ruiz   +9 more
openaire   +3 more sources

Treatments and overall survival in patients with Krukenberg tumor

Archives of Gynecology and Obstetrics, 2019
Krukenberg tumor (KT) is a rare secondary ovarian tumor, primarily localized at the gastrointestinal tract in most cases. KT is related to severe prognosis due to its aggressiveness, diagnostic difficulties and poor treatment efficacy. Several treatments have been used, such as cytoreductive surgery (CRS), adjuvant chemotherapy (CT) and/or hyperthermic
Lionetti, Ruggero, De Luca, Marcello, Travaglino, Antonio, Raffone, Antonio, Insabato, Luigi, Saccone, Gabriele, Mascolo, Massimo, D'armiento, Maria, Zullo, Fulvio, Corcione, Francesco   +9 more
openaire   +4 more sources