Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Impact of age on graft-versus-host disease and overall survival in pediatric hematopoietic cell transplant recipients. [PDF]
Nishitani M +23 more
europepmc +1 more source
ABCB1 Polymorphisms Influence on Temozolomide Resistance and Overall Survival in Glioblastoma Patients: A Systematic Review of Clinical Evidence. [PDF]
De Luca F +7 more
europepmc +1 more source
Prognostic Superiority of the White Cell-to-Lymphocyte Ratio (WLR) in Predicting Overall Survival in Patients With Gliomas. [PDF]
Zhang X, Cai G, Zhang H, Zhang Y.
europepmc +1 more source
Time to treatment initiation and overall survival in osteosarcoma: a national cancer database analysis. [PDF]
Farmer SH +3 more
europepmc +1 more source
Prediction of Overall Survival in Glioblastoma Using Early Postoperative Reduction in FLAIR Lesion Volume After Gross Total Resection. [PDF]
Aoki T +9 more
europepmc +1 more source
Overall survival and prognostic factors in young women with breast cancer: a retrospective cohort study from Southern Thailand. [PDF]
Khongthong P +2 more
europepmc +1 more source
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Cancer Discovery, 2023Abstract The final overall survival (OS) results for the ADAURA trial show that osimertinib reduces the risk of death by 51% in patients with EGFR-mutated non–small cell lung cancer. For stage II or IIIA disease, the 5-year OS was 85% in patients who received osimertinib and 73% in the control group.
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Concordance index: Surrogacy of progression-free survival for overall survival
Contemporary Clinical Trials, 2021In oncology clinical trials, the primary endpoint is often time to an event of clinical interest, e.g., time to disease progression or time to death. As a result, progression-free survival (PFS: the time from initiation of treatment till disease progression or death whichever occurs first) and overall survival (OS: the time from initiation of treatment
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Overall survival in older patients with cancer
BMJ Supportive & Palliative Care, 2018ObjectivesA growing number of patients with cancer are older adults. We sought to identify the predictors for overall survival (OS) in older adults with solid tumour and haematological malignancies between January 2013 and December 2016.MethodsRetrospective cohort study.
Beatrice J Edwards +11 more
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