Results 91 to 100 of about 320,909 (424)

Estimating Heterogeneous Causal Effect of Polysubstance Usage on Drug Overdose from Large-Scale Electronic Health Record [PDF]

arXiv, 2021
Drug overdose has become a public health crisis in the United States with devastating consequences. However, most of the drug overdose incidences are the consequence of recitative polysubstance usage over a defined period of time which can be happened by either the intentional usage of required drug with other drugs or by accident. Thus, predicting the
arxiv  

Dose Finding with Escalation with Overdose Control (EWOC) in Cancer Clinical Trials [PDF]

Statistical Science 2010, Vol. 25, No. 2, 217-226, 2010
Traditionally, the major objective in phase I trials is to identify a working-dose for subsequent studies, whereas the major endpoint in phase II and III trials is treatment efficacy. The dose sought is typically referred to as the maximum tolerated dose (MTD).
arxiv   +1 more source

Drug Overdose Mortality Among People Experiencing Homelessness, 2003 to 2018

JAMA Network Open, 2022
This cohort study describes the death rates and drug types involved in fatal drug overdoses in the past 15 years among individuals experiencing homelessness in Boston, Massachusetts.
Danielle R. Fine, Kirsten A Dickins, Logan D. Adams, Denise de Las Nueces, Karen Weinstock, Joseph Wright, Jessie M. Gaeta, Travis P. Baggett   +7 more
semanticscholar   +1 more source

Supercompliant Lattice Boosts n‐type AgSbTe2 Thermoelectrics

Advanced Functional Materials, EarlyView.
The supercompliant lattice design enables the first realization of n‐type electrical transport in AgSbTe2 by overcoming intrinsic electron‐killer defects and exceeding the doping limits imposed by the conventional Hume–Rothery rule. Accordingly, the best performance n‐type Ag0.8Na0.3Sb0.6Bi0.4Te2 sample achieves a low κ of 0.27 W·m−1·K−1 that ...
Ruoyan Li, Shuai Han, Chunyu Zhang, Suyao Liu, Wen Yin, Yuanguang Xia, Pengfei Liu, Zhen‐Hua Ge, Dongyao Zhao, Bingchao Yang, Lulu Huang, Zhi Zhang, Yongsheng Zhang, Yuan Yu, Bangzhi Ge, Chongjian Zhou   +15 more
wiley   +1 more source

Overdose experiences among injection drug users in Bangkok, Thailand

Harm Reduction Journal, 2010
Background Although previous studies have identified high levels of drug-related harm in Thailand, little is known about illicit drug overdose experiences among Thai drug users.
Wood Evan, Kaplan Karyn, Suwannawong Paisan, Hayashi Kanna, Fairbairn Nadia, Milloy M-J, Kerr Thomas   +6 more
doaj   +1 more source

Provider Education & Requirements for Opioid Prescriptions [PDF]

, 2017
Nationally, there has been a surge in the opioid prescription crisis with associated overdose deaths. Vermont is no exception, with increasing opioid overdose related deaths within the last 10 years.
Leung, Lawrence J
core   +1 more source

Homeless drug users' awareness and risk perception of peer "Take Home Naloxone" use – a qualitative study [PDF]

, 2006
BACKGROUND Peer use of take home naloxone has the potential to reduce drug related deaths. There appears to be a paucity of research amongst homeless drug users on the topic.
A Edwards, A Jones, B Powis, D Best, D Bigg, Department of Health, H Joffe, HMSO, J Fountain, J Strang, J Strang, K Dettmer, Katharine Francis, Lesley Jones, M Gossop, N Wright, N Wright, Nat Wright, Nicola Oldham, NMAC, NS Oldham, O Renn, PT O' Driscoll, S Darke, SR Lenton, T Beswick, T Greenhalgh, World Health Organisation   +27 more
core   +3 more sources

Biomimetic Nanomedicines Deliver Naringin for Enhanced Acute Liver Failure Therapy via Balanced Regulation of Hepatocyte Oxidative Stress and Kupffer Cell Inflammation

Advanced Functional Materials, EarlyView.
A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao, Maoze Wang, Jinling Huang, Yu Wang, Jing Zhao, Ran Wang, Zhi Ping Xu, Jianping Jiang, Lingxiao Zhang   +8 more
wiley   +1 more source

Overdose prevention activities led by local public health departments, 2019–2023

Substance Abuse Treatment, Prevention, and Policy
Background Drug overdose deaths in the United States increased to historic levels in recent years, with provisional estimates indicating more than 111,000 deaths in the 12 months ending July 2023. In 2019, the Centers for Disease Control and Prevention’s
April Wisdom, Stephanie Haddad, Madhumita Govindu, Francis Higgins, Nikki Filion, Kate Sullivan, Cherie Rooks-Peck   +6 more
doaj   +1 more source

A statistical analysis of drug seizures and opioid overdose deaths in Ohio from 2014 to 2018 [PDF]

Journal of Student Research, Volume 10, Issue 1, 2021
This paper examines the association between police drug seizures and drug overdose deaths in Ohio from 2014 to 2018. We use linear regression, ARIMA models, and categorical data analysis to quantify the effect of drug seizure composition and weight on drug overdose deaths, to quantify the lag between drug seizures and overdose deaths, and to compare ...
arxiv   +1 more source