Results 91 to 100 of about 345,181 (405)

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

open access: yesAdvanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim   +5 more
wiley   +1 more source

Impact of COVID-19 on Opioid Prescribing, Consumption, Pain, and Outcomes after Surgery

open access: yesAnnals of Surgery Open
Objective:. The aim is to compare opioid prescription, consumption, and patient-reported and clinical outcomes after surgical discharge pre- versus post-COVID-19 pandemic. Background:.
Dorna Kheirabadi, MD   +6 more
doaj   +1 more source

Loperamide Overdose [PDF]

open access: yesCureus, 2019
In light of the opioid epidemic, cardiac complications following a loperamide overdose are a growing concern for patients presenting to the emergency department (ED). Here, we present the case of a 35-year-old male with long QT syndrome who presented following a loperamide overdose and was receiving multiple shocks because of the resulting arrhythmias ...
Arnold, Casey   +1 more
openaire   +2 more sources

Disparities by Sex and Race and Ethnicity in Death Rates Due to Opioid Overdose Among Adults 55 Years or Older, 1999 to 2019

open access: yesJAMA Network Open, 2022
Key Points Question Is there variation by sex and by racial and ethnic subgroups in rates of opioid overdose deaths among older adults over time? Findings In this cross-sectional study of opioid overdose deaths in older adults from 1999 to 2019, 79 893 ...
Maryann Mason   +3 more
semanticscholar   +1 more source

A Heparin‐Functionalized Scaffold with HB‐EGF Immobilization for Tissue Engineering

open access: yesAdvanced Healthcare Materials, EarlyView.
In this study, a heparin‐functionalized scaffold is designed for bio‐mimicking growth factors reservoir function of extracellular matrix. Due to the presence of heparin‐binding domain, heparin‐binding epidermal growth factor‐like growth factor (HB‐EGF) is effectively and spatially captured by heparin‐functionalized scaffold.
Bowu Peng   +8 more
wiley   +1 more source

Predictors of future overdose among people who inject drugs in Baltimore, Maryland

open access: yesDrug and Alcohol Dependence Reports
Background: Longitudinal studies of future overdose risk among people who inject drugs (PWID) are needed to inform planning of targeted overdose preventions in the United States.
Michael P. Ramirez   +11 more
doaj   +1 more source

Development of a Novel Synthetic Hydrogel Sealant for Effective Prevention of Liver Resection‐Associated Bile Leakage

open access: yesAdvanced Healthcare Materials, EarlyView.
A dual‐crosslinking poly(ethylene glycol) (PEG) hydrogel is presented that rapidly solidifies and progressively adheres to tissue, achieving durable sealing of bile leaks. In hepatectomy models, this system prevents postoperative complications more effectively than conventional sealants, highlighting its translational potential as a safe and efficient ...
Kazuyoshi Matsubara   +7 more
wiley   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

open access: yesAdvanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen   +9 more
wiley   +1 more source

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