Results 241 to 250 of about 320,909 (424)

Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose

Archives of Toxicology, 2022
J. Akakpo, A. Ramachandran, S. Curry, B. Rumack, H. Jaeschke   +4 more
semanticscholar   +1 more source

Alemtuzumab Exposure and T Lymphocyte Depletion: A Population Pharmacokinetic‐Pharmacodynamic Model of Alemtuzumab Induction Therapy for Kidney Transplantation

Clinical Pharmacology &Therapeutics, EarlyView.
Alemtuzumab is a T cell‐depleting monoclonal antibody that is used for the prevention of kidney transplant rejection. The duration of lymphodepletion after the current standard induction therapy dose is likely longer than necessary, resulting in prolonged T cell lymphopenia with the associated risk of infections. Here, the interplay between alemtuzumab
Lukas K. van Vugt, Tom C. Zwart, Suzanne Bezstarosti, Sebastiaan Heidt, Marlies E. J. Reinders, Dennis A. Hesselink, Aiko P. J. de Vries, Brenda C. M. de Winter, Dirk Jan A. R. Moes   +8 more
wiley   +1 more source

Sodium bicarbonate and hyperventilation in treating an infant with severe overdose of tricyclic antidepressant. [PDF]

, 1984
DavidS. Hodes
openalex   +1 more source

Reply to: Methotrexate toxicity and glucarpidase: A call for dose optimization. Koppen A, et al. Br J Clin Pharmacol. 2025;91(5):1289‐1292 doi:10.1002/bcp.70044

British Journal of Clinical Pharmacology, EarlyView.
Carmelo Rizzari, Stefan Schwartz
wiley   +1 more source

Changes in Protein Expression of Renal Drug Transporters and Drug‐Metabolizing Enzymes in Autosomal Dominant Polycystic Kidney Disease Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Autosomal dominant polycystic kidney disease is the most prevalent inherited kidney disease and leads to bilateral kidney enlargement and progressive loss of renal function, often over decades. Comorbidities include hypertension, flank pain, and bacterial infections. The condition often necessitates prolonged multidrug therapy.
Annika C. Tillmann, Dorien J. M. Peters, Amin Rostami‐Hodjegan, Patricia Wilson, Jill Norman, Jill Barber, Zubida M. Al‐Majdoub   +6 more
wiley   +1 more source

Urine discoloration after acetaminophen overdose. [PDF]

, 1986
P M Clark, J. David Clark, T. Wheatley
openalex   +1 more source

Sociodemographic and clinical characteristics associated with overdose among patients with a substance-related diagnosis in the emergency department of Southern California. [PDF]

Harm Reduct J
Maila B, Zúñiga ML, Marienfeld C.
europepmc   +1 more source

Engagement in a National Naloxone Programme among people who inject drugs [PDF]

, 2016
Bird, Sheila M., Goldberg, David, Hutchinson, Sharon J., McAuley, Andrew, Munro, Alison, Taylor, Avril   +5 more
core   +2 more sources

Rapid Analytical Method for Quantification of Gamma‐Hydroxybutyrate (GHB) in Hair by UPLC‐MS/MS

Drug Testing and Analysis, EarlyView.
A rapid and simple UPLC‐MS/MS method for quantification of GHB in 10 mg of hair was developed. The method was satisfactorily validated, showing a linear range of 0.5–50 ng/mg, which allows us to quantify endogenous and exogenous GHB concentrations.
Miriam Blanco‐Ces, Ana de‐Castro‐Rios, Angela Lopez‐Rabuñal, Maria Cobo‐Golpe, Angelines Cruz, Elena Lendoiro   +5 more
wiley   +1 more source

Effects of massive overdose of epidural morphine sulphate [PDF]

, 1982
Pamela J. Masoud, Cloid D. Green
openalex   +1 more source