Results 111 to 120 of about 907,993 (350)

Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes

open access: yesAdvanced Healthcare Materials, EarlyView.
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu   +6 more
wiley   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

open access: yesAdvanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami   +4 more
wiley   +1 more source

The Age‐Dependent Resident Myonuclear Multi‐Omic Response to an Acute Skeletal Muscle Hypertrophic Stimulus in Mice

open access: yesAdvanced Science
A detailed analysis of how muscle fiber nuclei (myonuclei) respond to a hypertrophic stimulus could provide a critical step toward understanding compromised skeletal muscle plasticity with age.
Pieter J. Koopmans   +8 more
doaj   +1 more source

Dynamic Response Analysis of Parallel Twin Tunnels Under Different Train Loads

open access: yesApplied Sciences
Due to the spatial constraints of underground environments, the spacing between dual-line tunnels in urban metro systems is often limited, leading to potential mutual interference during the operation of trains in closely spaced parallel tunnels. In this
Lin Wu   +3 more
doaj   +1 more source

Interruption overload: telephones in Ford Madox Ford’s "4692 Padd", "A Call" and "A Man Could Stand Up" [PDF]

open access: yes, 2013
Ford Madox Ford’s short story “‘4692 Padd’” (1908), his novella A Call (1910), and his novel A Man Could Stand Up— (1926) all exploit the narratological potential of the rhetorical tropes of interruption.
McLoughlin, Kate
core  

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He   +10 more
wiley   +1 more source

Smart distribution board overload detector by using microcontroller [PDF]

open access: yes, 2020
A statistic by Economic Planning Unit (EPU) on the electricity growth in Malaysia has shown an increment in line with economic growth [1]. In line with government policies, the energy supply industry has been molding itself to cater to the rapid ...
Ismail, Muhammad Nafis   +4 more
core  

Investigating design features of a computer-mediated communication system [PDF]

open access: yes, 2007
Computer-mediated communication (CMC) is increasingly used in higher education, but it is not without problems. The effectiveness of CMC depends on many factors, including the characteristics of CMC systems themselves.
Kear, Karen Lesley
core   +1 more source

Atherosclerosis is aggravated by iron overload and ameliorated by dietary and pharmacological iron restriction.

open access: yesEuropean Heart Journal, 2019
AIMS Whether and how iron affects the progression of atherosclerosis remains highly debated. Here, we investigate susceptibility to atherosclerosis in a mouse model (ApoE-/- FPNwt/C326S), which develops the disease in the context of elevated non ...
F. Vinchi   +11 more
semanticscholar   +1 more source

Modular Control of PEG‐Poly(2‐Oxazoline) Co‐Assembly Enables Tunable Aggregate Properties for Intraocular Pressure Management

open access: yesAdvanced Healthcare Materials, EarlyView.
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka   +2 more
wiley   +1 more source

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