Results 151 to 160 of about 644,869 (286)

Gentiopicroside Regulates EGFR and Induces Its Lysosomal Degradation to Attenuate Heart Failure

Phytotherapy Research, EarlyView.
GPS attenuates pressure overload‐induced cardiac remodeling by promoting lysosomal degradation of EGFR. TAC‐induced EGFR accumulation activates AKT/ERK1/2 signaling and drives pathological cardiac hypertrophy, fibrosis, apoptosis, oxidative stress, and cardiac dysfunction. GPS promotes lysosome‐dependent EGFR degradation, thereby limiting excessive AKT/
Mingzhen Cao, Da Ke, Jian Ni, Yuan Yuan, Zhang Nan, Xiujun Dai, Heng Zhou   +6 more
wiley   +1 more source

Data-driven rapid assessment of bridge responses under mixed traffic with restricted overloaded vehicles using machine learning. [PDF]

PLoS One
Luo B, Li Q, Wang J, Wang G, Wu J, Wang Z, Zhan C.   +6 more
europepmc   +1 more source

The design of weight enforcement strategies for overloaded heavy-goods vehicles on complex road networks

, 2018
Overloaded heavy-goods vehicles result in road infrastructure life-time reduction, market distortion and road safety reduction. Analysis of the motivations for overloading showed that competition serves as a strong motivation for companies to overload ...
van Velzen, Martijn (author)
core  

Environmental pollution and sustainable restoration of the Yamuna River: A review of water quality, health risks, and phycoremediation

River, EarlyView.
Abstract The Yamuna River, one of India's most significant river systems and the largest tributary of the Ganges River, serves critical ecological, socio‐economic, and cultural functions. However, rapid urbanization, industrialization, and intensive agriculture have severely degraded its water quality, resulting in extensive pollution with untreated ...
Dharmendra Kumar, Gaurav Kumar, Elangbam Geetanjali, Rashmi Shakya, Deepali Verma, Shivankar Agrawal, Dinabandhu Sahoo   +6 more
wiley   +1 more source

Failure Analysis for Overall Overturning of Concrete Single-Column Pier Bridges Induced by Temperature and Overloaded Vehicles. [PDF]

Materials (Basel)
Wang Y, Zhou Y, Xue Y, Yao C, Wang K, Luo X.   +5 more
europepmc   +1 more source

Automatic Measurement of Payload for Prevention of Overloading in Heavy Vehicles

Overloading of heavy vehicles results in road damage, short vehicle life, and vehicle manoeuvre difficulty. Heavy vehicle accidents may also cause serious casualties. Therefore, in addition to careful driving, overload avoidance of heavy vehicles is also an important issue in preventing traffic accidents.
openaire   +1 more source

Blockchain and Food Trust: Will Consumers Pay More?

Sustainable Development, EarlyView.
ABSTRACT Blockchain is increasingly used in agri‐food supply chains to make products more transparent and trustworthy. Yet, in countries like Italy, where certifications such as PDO, PGI, and organic labels already shape consumer confidence, its added value is still unclear.
Federico Modica, Filippo Sgroi, Giusi Giamporcaro, Caterina Sciortino   +3 more
wiley   +1 more source

Instability detection and overload controlling system: a case of public transportation. [PDF]

Sci Rep
Kahsay BG, Nallamothu RB.
europepmc   +1 more source

National Policy Coherence Counts for Reducing Inequality in Global Climate and Development Agendas

Sustainable Development, EarlyView.
ABSTRACT International institutions promote policy coherence as crucial to the effective and fair implementation of global sustainability agendas, though the evidence for its benefits is slim. We present here the first systematic cross‐country dataset on the consequences of national government efforts to promote policy coherence for vulnerable groups ...
Katherine Browne, Adis Dzebo, Zoha Shawoo, Mario Cardenas, Pierrick Chalaye, Alexia Faus Onbargi, Cassilde Muhoza, Patricia Nicdao, Nokwethaba Makhanya, Navam Niles, Priyatma Singh   +10 more
wiley   +1 more source

Advances in research on layered double hydroxides for biomedical applications

Smart Molecules, EarlyView.
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang, Zhiping Zhang, Zhao Wang, Hao Zhang, Yen Leng Pak, Yingying Jing, Yurong Guo, Fang Li, Xiao Wang, Quanxiang Han, Lei Yu, Xuejiao Li, Xing Gao, Jibin Song   +13 more
wiley   +1 more source