Results 91 to 100 of about 847,152 (333)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

open access: yesAdvanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj   +21 more
wiley   +1 more source

'You Don't Know How Lucky You Are to Be Here!': Reflections on Covert Practices in an Overt Participant Observation Study [PDF]

open access: yes
There has been a tendency in sociology to see covert and overt roles of social researchers in participant observation studies as opposites. This is both in terms of the researcher role and the surrounding ethics, with the overt researcher role being seen
John S. McKenzie
core  

Westminster can learn a lot about gender equality by looking at Welsh and Scottish levels of political representation [PDF]

open access: yes, 2012
Discrimination and under-representation of women is still overt and visible in politics. Diana Silvia Stirbu argues that progress on the gender equality agenda doesn’t come easily, but it is possible through a combination of structural, political and ...
Stirbu, Diana Silvia
core  

Generation of an Induced Pluripotent Stem Cell‐Derived Alveolar Type II In Vitro Model to Study Influenza A Virus Infection and Drug Treatments

open access: yesAdvanced Healthcare Materials, EarlyView.
Patient‐specific induced pluripotent stem cells (iPSCs) can be differentiated into alveolar type II cells (iAT2s), expanded as 3D alveolospheres, and grown at physiologically relevant air–liquid interface (ALI). This study shows for the first time the infectability of iAT2s by the influenza A virus (IAV) and proves their responsiveness to the well ...
Lena Gauthier   +7 more
wiley   +1 more source

A computational approach to the covert and overt deployment of spatial attention [PDF]

open access: yes, 2008
Popular computational models of visual attention tend to neglect the influence of saccadic eye movements whereas it has been shown that the primates perform on average three of them per seconds and that the neural substrate for the deployment of ...
Alexandre, Frédéric   +2 more
core   +2 more sources

Signatures of Energy Flux in Particle Production: A Black Hole Birth Cry and Death Gasp [PDF]

open access: yes, 2015
It is recently argued that if the Hawking radiation process is unitary, then a black hole's mass cannot be monotonically decreasing. We examine the time dependent particle count and negative energy flux in the non-trivial conformal vacuum via the moving ...
Good, Michael R. R., Ong, Yen Chin
core   +3 more sources

Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis

open access: yesAdvanced Healthcare Materials, EarlyView.
Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.
Sabrina N. VandenHeuvel   +13 more
wiley   +1 more source

The Brain Differentially Prepares Inner and Overt Speech Production: Electrophysiological and Vascular Evidence

open access: yesBrain Sciences, 2020
Speech production not only relies on spoken (overt speech) but also on silent output (inner speech). Little is known about whether inner and overt speech are processed differently and which neural mechanisms are involved.
Franziska Stephan   +2 more
doaj   +1 more source

Nurses’ Perceptions of Horizontal Violence [PDF]

open access: yes, 2016
In this article, I describe a study exploring horizontal violence and nurses’ perceptions of the phenomenon within the context of two 28-bed inpatient hospital units. The purpose of the study was to develop a clearer understanding of horizontal violence,
Taylor, Rosemary A.
core   +3 more sources

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre   +3 more
wiley   +1 more source

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