Results 131 to 140 of about 847,152 (333)
Advanced Science, EarlyView.Utilizing a mitochondrial double‐targeted strategy, a novel near‐infrared fluorescent probe (FTZ‐2) is established for monitoring viscosity variations in ferroptosis‐mediated drug‐induced liver injury. In summary, this work provided a practical strategy for the early diagnosis and evaluation of liver injury.
Yongqing Zhou +5 more
wiley +1 more source
Revista Brasileira de AnestesiologiaBackground and objective Prediction of postoperative excessive blood loss is useful for management of Intensive Care Unit after cardiac surgery. The aim of present study was to examine the effectiveness of International Society on Thrombosis and ...
Yoon Ji Choi +7 more
doaj +1 more source
Advanced Science, EarlyView.Homoisoflavanone (HIF), a bioactive compound isolated from Polygonatum kingianum, selectively suppresses colorectal cancer progression by inducing DNA damage‐mediated mitochondrial apoptosis and parthanatos‐like cell death. HIF triggers mitochondrial dysfunction, including depolarized membrane potential, elevated ROS, and ATP depletion, while impairing
Hongjie Fan +12 more
wiley +1 more source
Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System
Advanced Science, EarlyView.This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi +13 more
wiley +1 more source
Studies in African LinguisticsThis paper presents data from Gã (Kwa, Niger-Congo language spoken in Ghana) that show that controlled subjects of non-finite predicates must be overt in this language.
Deborah Allotey, Ileana Paul
doaj
Advanced Science, EarlyView.Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang +16 more
wiley +1 more source
Null Subjects in Northeast English [PDF]
, 2011 This paper presents data and analysis relating to null subjects in spoken colloquial English. While English is not a „pro-drop? language (i.e.
Bailey, Laura R.
core
METTL5 Enables Immune Evasion of Liver Cancer via Chemokine mRNA Translation Regulation
Advanced Science, EarlyView.METTL5 reshapes the tumor immune microenvironment through ribosome 18S rRNA m6A modification to regulate the translation of chemokine mRNA. Targeting METTL5‐mediated immunosuppression unleashes anti‐tumor immunity and improves the efficacy of anti‐PD‐1 therapy.
Shuang Li +19 more
wiley +1 more source
From pronounced to imagined: improving speech decoding with multi-condition EEG data
Frontiers in NeuroinformaticsIntroductionImagined speech decoding using EEG holds promising applications for individuals with motor neuron diseases, although its performance remains limited due to small dataset sizes and the absence of sensory feedback. Here, we investigated whether
Denise Alonso-Vázquez +4 more
doaj +1 more source
A saliency-based search mechanism for overt and covert shifts of visual attention
Vision Research, 2000 L. Itti, C. Koch
semanticscholar +1 more source