Results 121 to 130 of about 924,903 (427)

Dual‐Locking the SARS‐CoV‐2 Spike Trimer: An Amphipathic Molecular “Bolt” Stabilizes Conserved Druggable Interfaces for Coronavirus Inhibition

open access: yesAdvanced Science, EarlyView.
A new amphipathic molecule, S416 is discovered, that locks the SARS‐CoV‐2 spike protein in its closed state, blocking viral entry. S416 acts as a molecular bolt, binding six sites: three between adjacent RBDs and three connecting NTDs to RBDs. This dual‐locking mechanism stiffens the spike structure and reduces its flexibility.
Shiliang Li   +21 more
wiley   +1 more source

Changes in the nutritional status of Bolivian women 1994-1998: demographic and social predictors [PDF]

open access: yes, 2004
Introduction: Bolivia, as one of the poorest Latin American countries, has dealt with the problems of undernutrition for the last 50 y. Little importance has been given to the increase in overweight and obesity among the population, despite the ...
Kolsteren, Patrick   +1 more
core   +1 more source

Prevalence of obesity and its associated factors in population aged 20 to 70 years in urban areas of Mazandaran [PDF]

open access: yesJournal of Mazandaran University of Medical Sciences, 2006
Background and purpose: Obesity is an undesirable outcome of changing of life style and behavior. In order to control obesity associated diseases, this study was aimed to determine the prevalence of obesity and its associated factors in population aged ...
B. Heydari, K. Hajian
doaj  

Relationship between Periodontal disease and Asthma among overweight/obese adults [PDF]

open access: yesarXiv, 2016
Aim: To assess the relationship between oral health and asthma. Methods: Data from 1,315 overweight or obese individuals, aged 40-65 years was used. Asthma was self-reported, while periodontitis, bleeding on probing (BOP), and plaque index were determined by clinical examinations. Results: Using logistic regression adjusting for gender, smoking status,
arxiv  

Tipping Elements in the Human Intestinal Ecosystem [PDF]

open access: yes, 2014
Recent studies show that the microbial communities inhabiting the human intestine can have profound impact on our well-being and health. However, we have limited understanding of the mechanisms that control this complex ecosystem. Based on a deep phylogenetic analysis of the intestinal microbiota in a thousand western adults we identified groups of ...
arxiv   +1 more source

A multicenter study of body mass index in cancer patients treated with anti-PD-1/PD-L1 immune checkpoint inhibitors: when overweight becomes favorable

open access: yesJournal of Immunotherapy for Cancer, 2019
BackgroundRecent evidence suggested a potential correlation between overweight and the efficacy of immune checkpoint inhibitors (ICIs) in cancer patients.Patients and methodsWe conducted a retrospective study of advanced cancer patients consecutively ...
A. Cortellini   +44 more
semanticscholar   +1 more source

A Touch Enabled Hemodynamic and Metabolic Monitor

open access: yesAdvanced Science, EarlyView.
This work presents a touch‐based hybrid platform for simultaneous monitoring of vital signs and sweat metabolites. With a simple tri‐finger touch of 4–6 min, users can concurrently get to know their glucose, uric acid, cortisol levels from fingertip sweat, along with blood pressure and heart rate.
Omeed Djassemi   +19 more
wiley   +1 more source

Childhood Overweight and Obesity and Associated Factors in Iranian Children and Adolescents: A Multilevel Analysis; the CASPIAN-IV Study

open access: yesFrontiers in Pediatrics, 2018
Objective: The purpose of this paper is to explore multidimensional factors related to childhood obesity and overweight based on the data gathered on different aspects of the general health status were assessed among a large number of Iranian children ...
Patricia Khashayar   +10 more
doaj   +1 more source

Analyzing the Language of Food on Social Media [PDF]

open access: yes, 2014
We investigate the predictive power behind the language of food on social media. We collect a corpus of over three million food-related posts from Twitter and demonstrate that many latent population characteristics can be directly predicted from this data: overweight rate, diabetes rate, political leaning, and home geographical location of authors. For
arxiv   +1 more source

Subgenome Dominance in Allotetraploid Actinidia valvata Regulates RNA m6A Modification for Waterlogging Tolerance

open access: yesAdvanced Science, EarlyView.
The waterlogging tolerance of allotetraploid Actinidia valvata is inherited from one of its diploid progenitors, which leads to subgenome expression dominance, mediated by complex mechanisms including altered chromatin accessibility and DNA methylation.
Xiaoli Hu   +14 more
wiley   +1 more source

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