Results 241 to 250 of about 955,210 (402)

Overweight and Obesity and the Demand for Primary Physician Care [PDF]

open access: yes
The standard economic model for the demand for health care predicts that unhealthy behaviour such as being overweight or obese should increase the demand for medical care, particularly as clinical studies link obesity to a number of serious diseases.
Datta Gupta, Nabanita, Greve, Jane
core  

VALIDITY OF A NON-EXERCISE VO2 MAX PREDICTION MODEL FOR OVERWEIGHT WOMEN

open access: bronze, 1995
Kimberly A. DeMers   +7 more
openalex   +1 more source

A Pharmacometric Method for Quantitative Determination of Improvement in Body Composition and Characterization of the Exposure–Response Relationship during Treatment of Obesity with Tirzepatide

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
About half of the world's population is living with overweight or obesity. Tirzepatide is an approved treatment for chronic weight management. We sought to characterize the exposure–response relationship for weight reduction in patients with overweight or obesity and quantify the associated changes in body composition.
Emmanuel Chigutsa   +4 more
wiley   +1 more source

Re‐Evaluation of Fixed Dosing Versus Body Size‐Based Dosing Approaches for Large Molecule Therapeutics in Adults

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Wang et al.1 (2009) and Zhang et al.2 (2011) recommended a fixed dosing approach for large molecule therapeutics for first‐in‐human (FIH) trials, based on the finding that the majority of α values (body size effect on clearance) were < 0.5 across 12 monoclonal antibodies (mAbs) and 18 therapeutic proteins (TPs) and peptides, and fixed dosing provides ...
Andrew B. SyBing   +2 more
wiley   +1 more source

Bahaman patch reefs: Numerous and neglected

open access: yesThe Depositional Record, EarlyView.
Abstract Phanerozoic patch reefs are extensively studied because they are abundant and are potential reservoirs for valuable fluids. In contrast, geologic studies of modern reefs have largely focused on platform margins, leaving patch reefs comparatively neglected. What conditions favour patch‐reef development?
Paul Enos, Clay Robertson
wiley   +1 more source

Weight Gain Continues in the 1990s: 10-year Trends in Weight and Overweight from the CARDIA Study [PDF]

open access: bronze, 2000
Cora E. Lewis   +6 more
openalex   +1 more source

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