A Unique Case of Testicular Compromise in a Patient with Ovotesticular Disorder of Sexual Development and a Solitary Testicle [PDF]
Ovotesticular disorder of sexual development (OT-DSD), previously true hermaphroditism, is a condition in which one or both gonads contain testicular and ovarian tissue.
Ethan Vargo +2 more
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Two cases of late-diagnosed ovotesticular disorder of sex development.
Ovotesticular disorder of sex development (ovotesticular DSD) is defined as the presence of testicular and ovarian tissue in the same individual. Both external and internal genitalia of patients with ovotesticular DSD display a spectrum of phenotypes. Most children present with ambiguous genitalia in combination with unilateral or bilateral undescended
Eiji, Hisamatsu +2 more
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The ERK1/2 pathway regulates testosterone synthesis by coordinately regulating the expression of steroidogenic enzymes in Leydig cells [PDF]
Adult mice with a Leydig cell specific deletion of MAPK kinase (MEK) 1 and 2 (Mek1(f)(/)(f);Mek2(-/-);Cre(+)) mice display Leydig cell hypoplasia and hypergonadotropic hypogonadism.
Ascoli, Mario +2 more
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Three cases of primary amenorrhoea [PDF]
Three interesting series of cases in young ladies who reported with history of primary amenorrhoea with surprisingly different presentation, symptoms, clinical signs and findings requiring two entirely different algorithms which this article attempts to ...
Devi, L. Thulasi
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SRY-positive 78, XY ovotesticular disorder of sex development in a wolf cloned by nuclear transfer
Recently, we reported the three wolves cloning with normal karyotype from somatic cells of endangered male gray wolves (Canis lupus), but one wolf had female external genitalia. In this study, we conducted further clinical, histological, and genetic analyses. This cloned wolf had a normal uterus but developed ovotestis.
Kang, Jung Taek +9 more
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The Two Laws of Sex Stereotyping [PDF]
This Article offers two main contributions to the study of sex stereotyping. First, it identifies an organizing principle that explains why some forms of sex stereotyping are today legally prohibited while others are not. Second, it argues for a shift in
Ben-Asher, Noa
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Genetic Analysis for the Diagnosis of Disorders of Sexual Development in Indonesia [PDF]
Disorders of sex development (DSD) is defined by congenital conditions in which development of chromosomal, gonadal, or anatomical sex is atypical, while in clinical practice this term means any abnormality of the external genitalia.
Faradz, Sultana MH
core +3 more sources
A genomic atlas of human adrenal and gonad development [version 1; referees: awaiting peer review] [PDF]
Background: In humans, the adrenal glands and gonads undergo distinct biological events between 6-10 weeks post conception (wpc), such as testis determination, the onset of steroidogenesis and primordial germ cell development.
Achermann, JC +9 more
core
A rare case of 46XX ovotesticular disorder of sex development
Reddy, Sagar S.L., Subrahmanyam, K.A.V.
openaire +2 more sources

