Results 151 to 160 of about 971 (183)

Long‐term outcome of ovotesticular disorder of sex development: A single center experience

International Journal of Urology, 2011
Objectives:  To describe the clinical features of children with ovotesticular disorder of sex development (DSD) and to review cases of ovotesticular DSD in Japan.Methods:  Medical records of eight children diagnosed with ovotesticular DSD at our institute during the past 17 years were retrospectively evaluated.
Futoshi, Matsui, Kenji, Shimada, Fumi, Matsumoto, Toshihiko, Itesako, Keigo, Nara, Shinobu, Ida, Masahiro, Nakayama   +6 more
openaire   +2 more sources

The Genetics of Ovotesticular Disorders of Sex Development

2011
Disorders of sex development (DSD) encompass a very large spectrum of phenotypes, from minor malformations of the genitalia (hypospadias, cryptorchidism, and hypertrophy of the clitoris) to sexual ambiguity. Taken altogether, these anomalies have an estimated frequency of 0.5–1%.
openaire   +2 more sources

Regional Variations in the Management of Testicular or Ovotesticular Disorders of Sex Development

Sexual Development, 2011
Disorders of sex development arise in parts of the world with different socio-economic and cultural characteristics. We wished to determine the regional variations in the management of these conditions. A questionnaire was e-mailed to the 650 members of the European Society for Paediatric Endocrinology (ESPE), an international society with a mainly ...
N, Josso, L, Audi, G, Shaw
openaire   +2 more sources

The Spectrum of Ovotesticular Disorders of Sex Development in South Africa: A Single-Centre Experience

Hormone Research in Paediatrics, 2017
<b><i>Objective:</i></b> To describe the clinical characteristics, biochemistry, histopathology, and long-term outcomes in subjects with ovotesticular (OT) disorder of sex development (DSD). <b><i>Study Design:</i></b> This is a retrospective subset analysis of 64 cases of histologically confirmed OT DSD.
Yasmeen, Ganie, Colleen, Aldous, Yusentha, Balakrishna, Rinus, Wiersma   +3 more
openaire   +2 more sources

Long-Term Followup of a Large Cohort of Patients with Ovotesticular Disorder of Sex Development

Journal of Urology, 2014
We present the followup of a large cohort of patients with ovotesticular disorder of sex development treated at a single tertiary center.We reviewed the records of 20 patients with ovotesticular disorder of sex development. We retrospectively evaluated clinical and surgical characteristics.
Maria Helena Palma, Sircili, Francisco Tibor, Denes, Elaine Maria Frade, Costa, Marcos Giannetti, Machado, Marlene, Inacio, Rosana Barbosa, Silva, Miguel, Srougi, Berenice Bilharinho, Mendonca, Sorahia, Domenice   +8 more
openaire   +2 more sources

Ovotesticular Disorder of Sex Development (Ovotestis) in Simpson–Golabi–Behmel Syndrome: Expansion of the Clinical Spectrum

Pediatric and Developmental Pathology, 2018
Simpson–Golabi–Behmel syndrome type I (SGBS, OMIM312870), caused by defects of the GPC3 and GPC4 genes on chromosome Xq26, is an X-linked recessive macrosomia/multiple congenital anomaly disorder characterized by somatic overgrowth, coarse facial features, variable congenital anomalies, increased tumor risk, and mild-to-moderate neurodevelopmental ...
Monique E, De Paepe, Lawrence, Young, Julie R, Jones, Umadevi, Tantravahi   +3 more
openaire   +2 more sources

Ovotesticular Disorder of Sex Development: A Rare Case of Lateral Subtype 45X/46XY kariotype Diagnosed in Adulthood

Urology, 2019
A 53-year-old male referred to our centre because of hypergonadotropic hypogonadism detected during urological follow-up for urethral lithiasis. Physical examination showed short stature, micropenis, ambiguous external genitalia, and normal secondary sexual characteristics. Karyotype: 45 × 0/46XY.
Caputo M., Mele C., Zavattaro M., Sama M. T., Giordano M., Umari P., Volpe A., Aimaretti G., Prodam F.   +8 more
openaire   +4 more sources

53. Ovotesticular Disorder of Sex Development in Korean Children : Differentiating Ovotesticular Disorder of Sex Development from Others

Journal of Pediatric and Adolescent Gynecology, 2020
Sanghwa Kim, Inha Lee, Seok Kyo Seo, Sang Won Han, Yong Seung Lee, Bo Hyon Yun   +5 more
openaire   +1 more source

[Diagnosis and treatment of ovotesticular disorders of sex development in children].

Zhonghua nan ke xue = National journal of andrology, 2009
To investigate the diagnosis and treatment of ovotesticular disorders of sex development (DSD) in children.We reviewed the clinical data of 9 cases of ovotesticular DSD admitted in our department from 1988 to 2007.The patients ranged in age from 9 months to 9 years, 7 raised as males and 2 as females. As for the karyotype, 4 cases were 46,XX, 2 were 46,
Liang-Sheng, Lu, Shuang-Sui, Ruan, Yun-Li, Bi, Yi-Qun, Lu, Xiang, Wang, Lin-Juan, Ge, Xian-Min, Xiao   +6 more
openaire   +1 more source

Ovotesticular disorder of sex development: A rare cause of gynecomastia

Clinical History: A 13-year-old patient, raised as a boy, presented with gynecomastia and left-sided groin pain. On examination, the left scrotal sac was empty, with tenderness in the left groin. Pubic and axillary hair were present, and external genitalia consisted of a penis with hypospadias (Figures 1b and c).
openaire   +1 more source