Results 101 to 110 of about 1,336,223 (323)

Luteinizing hormone receptor knockout mouse: What has it taught us?

open access: yesAndrology, EarlyView.
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

open access: yesAndrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre   +5 more
wiley   +1 more source

What Moves Men to Change? A Mixed‐Methods Study on Facilitators and Barriers of Lifestyle Changes in Men Seeking Fertility Care

open access: yesAndrology, EarlyView.
ABSTRACT Background An unhealthy lifestyle negatively affects male fertility. Despite this, men that are part of an infertile couple often fail to improve their lifestyle and evidence on influencing factors is limited. Objectives To identify facilitators and barriers involved in lifestyle changes of men seeking fertility care and in lifestyle ...
Wiep R. de Ligny   +5 more
wiley   +1 more source

Testicular SIRT1 Loss Reveals an Aging‐Like Proteomic Landscape and Precipitates Reproductive Deterioration

open access: yesAndrology, EarlyView.
ABSTRACT Background Advanced paternal age is associated with reduced male fertility and testicular dysfunction. Among the molecular regulators involved in aging, SIRT1, a NAD+‐dependent deacetylase, plays a pivotal role in maintaining oxidative balance and cellular homeostasis.
María Iniesta‐Cuerda   +7 more
wiley   +1 more source

Is it safe to preserve uterus after live birth following progestin‐based fertility‐sparing treatment for endometrial cancer or atypical hyperplasia: A long‐term retrospective cohort study

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Achieving live birth following fertility‐sparing treatment is associated with improved recurrence‐free survival among patients with endometrial cancer/atypical endometrial hyperplasia. Abstract Introduction We aimed to assess the safety of continuous uterus‐preserving treatment among patients with endometrial cancer (EC) and atypical endometrial ...
Yiqin Wang   +9 more
wiley   +1 more source

Is combined letrozole and clomiphene superior to either as monotherapy: a systemic review and meta-analysis based on clinical trials

open access: yesGynecological Endocrinology
Objective This research was conducted to assess the therapeutic advantage of combined letrozole and clomiphene citrate versus monotherapy for polycystic ovarian syndrome (PCOS) patients.Study Design Five databases were searched using the search string ...
Anusha Ashkar   +5 more
doaj   +1 more source

Twin pregnancy with complete hydatidiform mole and coexisting fetus following ovulation induction with a non-prescribed clomiphene citrate regimen: a case report [PDF]

open access: gold, 2012
Sherif A. Shazly   +5 more
openalex   +1 more source

Three‐dimensional patient‐derived endometriosis model for drug evaluation

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
In this study, we developed a coculturing model with stromal cells and epithelial organoids to mimic the endometriotic lesion and for further evaluation of drug effects. Abstract Introduction Endometriomsis (EMs) is a complex and chronic gynecological disease characterized by distressing symptoms.
Yuqi Li   +10 more
wiley   +1 more source

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