A prospective randomized trial comparing dephereline and busereline for ovulation induction in heat-stressed lactating dairy cows. [PDF]
López-Gatius F.
europepmc +1 more source
Graphical abstract illustrating the barrier defense–tolerance framework of reproductive innate immunity. Across the female and male reproductive tracts and the maternal–fetal interface, epithelial barriers, innate sensors, immune cells, and microbial signals are integrated to preserve reproductive homeostasis.
Xianlin Rao +3 more
wiley +1 more source
Heterotopic Pregnancy Following Ovulation Induction With Successful Pregnancy Outcome: A Case Report. [PDF]
Ghimire U +5 more
europepmc +1 more source
Schematic workflow of the BioFET (biological field‐effect transistor)based hormone sensing system, including (1) 17β‐estradiol (E2) sample preparation in PBS (phosphate‐buffered saline), (2) DNA aptamerfunctionalized BioFET sensing, (3) electrical signal acquisition (IV: currentvoltage characteristics), and (4) machine‐learning (ML)based data analysis.
Alexandra Parichenko +9 more
wiley +1 more source
Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang +22 more
wiley +1 more source
The effect of ovulation induction with clomiphene citrate on pregnancy outcomes in patients with subclinical hypothyroidism: A retrospective study. [PDF]
Ince E +4 more
europepmc +1 more source
This study reveals a pivotal epigenetic regulatory role for the histone acetyltransferase p300, demonstrating that its acetylation of histone 3 at lysine 18 and 27 (H3K18ac and H3K27ac), alongside the formation of the p300/BRD4/SP1 complex, drives AR activation and ovarian fibrosis in PCOS.
Zhengquan Zhu +11 more
wiley +1 more source
Letrozole and clomiphene versus letrozole alone for ovulation induction in women with PCOS: a systematic review and meta-analysis. [PDF]
Eskandar K +6 more
europepmc +1 more source
Genetic Diagnosis and Discovery Enabled by Large Language Models
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu +25 more
wiley +1 more source
Outcomes of Secondary Ovulation Induction Following Failed Oocyte Pick-Up in In Vitro Fertilization (IVF) Cycles: A Retrospective Observational Study. [PDF]
Sendy F +3 more
europepmc +1 more source

