Results 121 to 130 of about 27,515 (301)

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Lactation, Childrearing, and Gender Justice

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT In this article, I discuss the significance of early infant feeding choices for the goal of gender justice. Focusing on human lactation practices, I identify Exclusive Gestational Nursing (EGN) as the norm in advanced industrial societies, which creates the expectation and permission for gestators, and only gestators, to nurse children, and ...
Jenny Brown
wiley   +1 more source

Plummer–Vinson syndrome in a 10‐year‐old boy from Côte d'Ivoire: An exceptional paediatric case with African context

open access: yesJPGN Reports, EarlyView.
Abstract Plummer–Vinson syndrome (PVS) is characterised by the triad of dysphagia, iron‐deficiency anaemia, and proximal oesophageal webs. While well described in adults, paediatric cases remain exceptionally rare, particularly in sub‐Saharan Africa.
Paul Mike Tayou Mbobda   +2 more
wiley   +1 more source

Mechanism of RNA‐Binding Protein ELAVL1 in Promoting Th2 Cell Differentiation Through Stabilizing CPA3 mRNA in Allergic Rhinitis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to elucidate the role of the RNA‐binding protein embryonic lethality abnormal vision‐like protein 1 (ELAVL1) in the pathogenesis of allergic rhinitis (AR), specifically by investigating its potential to promote T helper 2 (Th2) cell differentiation by regulating the stability of carboxypeptidase A3 (CPA3) mRNA.
Meng‐Ya Liu   +2 more
wiley   +1 more source

Glucocorticoids Impair the Airway Epithelial Barrier via Autophagy‐Associated Apoptosis in Asthma: A Preliminary Study Both In Vitro and In Vivo

open access: yesPediatric Discovery, EarlyView.
Mechanism underlying the negative effects of glucocorticoids on the airway epithelial barrier. Glucocorticoids upregulate autophagy factors and downregulate anti‐autophagy factors. Enhanced autophagy promotes excessive apoptosis and epithelial detachment, impairing airway barrier function.
Hao You   +10 more
wiley   +1 more source

Report on a Case of Blighted Ovum

open access: yes
Presenting in her late twenties, this case report examines a G6P2 patient at 11-weeks gestation that was diagnosed with a blightedovum, as well as the subsequent outcome and methods of additional management.
Aqsaa N. Chaudhry, MBA   +3 more
core  

Immunomodulatory Properties of Withania somnifera: Regulation of Innate Immune Cells and Clinical Implications

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Withania somnifera (L.) Dunal (WS), commonly known as Ashwagandha, is a prominent medicinal herb in Ayurveda, with extensive therapeutic potential attributed to its diverse phytochemical profile. This review critically examines the immunomodulatory properties of WS, focusing on innate immune cell populations, including neutrophils, eosinophils,
Rana Yukta   +9 more
wiley   +1 more source

Safe and Stable Germline Transmission of MSTN Mutations in Cattle. [PDF]

open access: yesAnim Genet
ABSTRACT With the global population expected to reach 10 billion by 2050, sustainable livestock production is critical. Gene editing of the myostatin (MSTN) gene represents a promising strategy to enhance muscle growth in cattle. In this study, MSTN‐mutated founder (F0) cows were used to generate F1 offspring via ovum pick‐up, in vitro fertilization ...
Gim GM   +10 more
europepmc   +2 more sources

A successful in vitro fertilization outcome in a hermaphrodite male

open access: yes
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 424-425, April 2025.
Shima Elbakhit M. E. Albasha   +2 more
wiley   +1 more source

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