Results 61 to 70 of about 56,247 (306)

Reducing the costs of floor cleaning in a level III NICU of Bangalore rural: a quality

BMJ Open Quality, 2022
Abhishek Somasekhara Aradhya, Venugopal Reddy, Praveen Venkatagiri, Latha Mercy   +3 more
doaj   +1 more source

The chicken embryo and its micro environment during egg storage and early incubation [PDF]

, 2008
When egg storage periods are prolonged (>7 days), hatchability and chick quality declines. The reason for this decline has been investigated, but is still not completely understood.
Brand, H., van den, Kemp, B., Meijerhof, R., Reijrink, I.A.M.   +3 more
core   +2 more sources

A Nanobody‐LNP Platform for Targeting and Relicensing Dendritic Cells for Potent Cancer Immunotherapy

Advanced Science, EarlyView.
Plastin‐2 (PLS2) is identified as a dual‐function receptor on DCs that mediates both nanoparticle uptake and immunomodulation. A nanobody‐LNP platform is engineered to integrate antigen delivery with relicensing DCs. The therapeutic strategy elicits potent anti‐tumor T cell responses and leads to significant inhibition of established tumors in vivo ...
Shugang Qin, Zhiying Huang, Hai Huang, Yupei Zhang, Yuting Chen, Xi He, Zhenyi Niu, Zhongzheng Xiang, Chaoyu Zou, Xiangrong Song   +9 more
wiley   +1 more source

Sustaining extended Kangaroo mother care in stable low birthweight babies in NICU: a quality improvement collaborative of six centres of Karnataka

BMJ Open Quality, 2023
, Shruthi K Bharadwaj, Abhishek Somasekhara Aradhya, Praveen Venkatagiri, Raksha Murthy, Anil Kallesh, Meena Jagadish, Poornachandra Rao, Divya Chandramouli, Doddarangaiah Hema, S N Chaithra, Hellan Glory, Jayashree Purkayastha, Dr. Srinath CS, Dr. Kamalakar, Ms. Asmath, Dr. Prashant, Dr. Dhananjay Sarji, Ms. Gayathri, Ms. Anusha Bai, Dr. Sushma, Dr. Nayana Singhekar, Dr. Vimal Kumar, Mrs. Pratima, Mrs. Dakshayani, Mrs. Sujatha, Mrs. Supritha   +26 more
doaj   +1 more source

Albumin‐Bound STING Agonist Reprograms HSPCs to Antitumor Neutrophils Enhancing CD8+ T Cell Immunity

Advanced Science, EarlyView.
This study demonstrates that an albumin‐bound STING agonist (Nano ZSA‐51D) reprograms HSPCs to produce antitumor neutrophils with enhanced MHC I–mediated CD8+ T cell activation, thereby sensitizing tumors to α‐PD1 therapy. These findings highlight a strategy to target early hematopoiesis for shaping neutrophil fate and potentiating cancer immunotherapy.
Jinsong Tao, Hong‐Yi Zhao, Chengyi Li, Hanning Wen, Fang Ke, Qiuxia Li, Miao He, Bo Wen, Zhongwei Liu, Kai Sun, Wei Gao, Duxin Sun   +11 more
wiley   +1 more source

Nano‐Enabled Systemic Delivery of STING Agonist by Engineered Silicasome for Potent Antitumor Immunotherapy

Advanced Science, EarlyView.
Engineered mesoporous silica nanoparticles (Silicasomes) enable systemic delivery of the STING agonist ADU‐S100, overcoming the instability and toxicity that limit cyclic dinucleotides to local administration. By enhancing tumor accumulation, activating systemic antitumor immunity, and remodeling the tumor immune microenvironment, these nanoparticles ...
Wenjing Zhou, Yuting Li, Xudong Sun, Honghong Yang, Xiayu Shi, Lijia Yao, Jinhong Jiang, Erli Wang, Haoyang Wang, Yi Wei, Xiangsheng Liu   +10 more
wiley   +1 more source

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

Advanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li, Lan Wang, Zihao Zhang, Chunmei Qian, Ning Li, Wei Huang, Qian Ba, Xiaojian Liu, Mayu Sun   +8 more
wiley   +1 more source

ASPIRAÇÃO FOLICULAR VIDEOLAPAROSCÓPICA COMPARATIVA EM OVELHAS DORPER E SANTA INÊS

Ciência Animal Brasileira, 2016
This study aimed to compare the number of aspirated follicles, recovered oocytes, oocyte quality and viability between Dorper and Santa Inês ewes submitted to the videolaparoscopic ovum pick-up.
Endrigo Adonis Braga de Araujo, Sidnei Nunes de Oliveira, Alexandre de Faria Tabet, Rodrigo Freitas Bittencourt, Marcos Chalhoub, Antonio de Lisboa Ribeiro Filho   +5 more
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

A rare case of swyer syndrome in two sisters with successful pregnancy outcome in both

Journal of Human Reproductive Sciences, 2019
Swyer syndrome is a disorder of sex development characterized by gonadal dysgenesis in a phenotypic female with normally developed Mullerian structures but a 46XY karyotype resulting from failure of testicular development in the early embryogenesis.
Anupam Gupta, Ritika Bajaj, Umesh N Jindal   +2 more
doaj   +1 more source