Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley +1 more source
School-level peer digital distraction, mathematics performance, creative thinking, and adolescent well-being across 80 education systems: global evidence from PISA 2022. [PDF]
Sung CM, Lin CH, Pan HH, Lin KF, Ho YC.
europepmc +1 more source
Proposed geothermal resources subzone
This application brought persuant to Title 13, Department of Land and Natural Resources, Sub-Title 7, Water and Land Development, Chapter 184, Designation and Regulation of Geothermal Resource Subzones, Subchapter 2, Designation of Geothermal Resource ...
Integrated Resources, Inc.
core
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Mental health literacy, self-regulatory fatigue, and attitudes toward aging among community-dwelling older adults with diabetes and their spouses: an actor-partner interdependence mediation model analysis. [PDF]
Yu P, Wu S, Zhou H, Wen Q.
europepmc +1 more source
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
Comparison of different solutions for applying patient-specific beam quality in treatment planning CT imaging. [PDF]
Sudár Á +6 more
europepmc +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Conversational AI and the Temporal Ecology of Self-Reflection. [PDF]
Kvietkute D.
europepmc +1 more source

