Results 81 to 90 of about 6,948,837 (250)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Natural resources: an alternative used as a complementary therapy by people who live with virus/immune-deficiency acquired syndrome, Tampico Tamaulipas, México

open access: yesCultura de los Cuidados, 2012
Aims: Were centred in understanding and explaining the meaning of natural resources for those people living with AIDS, from the perspective of anthropology of care, at the same time to determine which are those resources and their effectiveness from the ...
Socorro Piñones Martínez   +2 more
doaj   +1 more source

Water resources programs in Virginia

open access: yes, 1966
Held Oct. 6-7, 1966, Richmond, Va. Sponsored by Water Resources Research Center, Virginia Polytechnic InstituteIncludes the papers presented at the symposium and reports by the Division of Mineral Resources and by the U.S.

core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Couples’ Psychological Resources and Marital Satisfaction: The Mediating Role of Marital Support

open access: yesEurope's Journal of Psychology
The aim of this study was to assess the interdependent relations among psychological resources, marital support, and marital satisfaction in married couples from the perspective of both dyad members, using the Actor-Partner-Interdependence-Model (APIM ...
Keren Michael, Hasida Ben-Zur
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

ON THE CALCULATION OF THE SUCCESS RATE IN MINING [PDF]

open access: yesAnnals of the University of Petrosani: Economics, 2013
Mankind has always relied on resources. The mineral resources represent an important part of the resources required by the society. But mining has its own specificities, not only from technical point of view, but from economic point of view, tool ...
RAREŞ MUNTEANU
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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