Results 71 to 80 of about 747,270 (267)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Organization of on user’s own work with electronic resources, including remote ones
Библиосфера, 2010 Рассматриваются подходы к организации виртуального справочно-библиографического обслуживания в крупной научной библиотеке. Описывается одна из форм обслуживания – методическое сопровождение.
V. G. Svirjukova
doaj
Acta Universitatis Carolinae IuridicaThe European Union faces the challenge of ensuring its future budgetary stability, which relates to tendences to find new sources of budgetary revenues. From the perspective of EU objectives in sustainable development, it seems to be necessary to reflect
Ekkehart Reimer, Miroslava Večeř
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
EU own resources : momentum for a reform?
, 2016 The European institutions have been very timid about engaging in serious discussions on the financing system for the European project. The “own resources” dossier was already opened in 1962, together with the development of the first common policy and the reinforcement of the role of the European Parliament (EP).
openaire +4 more sources
Innovativeness and financial resources diversity of Slovenian early-stage enterpreneurs
Ekonomski Vjesnik, 2018 This paper focuses on the diversity of financial resources for Slovenian early-stage entrepreneurs. In the empirical study, we examined whether early-stage entrepreneurs with different characteristics regarding innovativeness also differ regarding the ...
Blaž Frešer, Polona Tominc
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Couples’ Psychological Resources and Marital Satisfaction: The Mediating Role of Marital Support
Europe's Journal of PsychologyThe aim of this study was to assess the interdependent relations among psychological resources, marital support, and marital satisfaction in married couples from the perspective of both dyad members, using the Actor-Partner-Interdependence-Model (APIM ...
Keren Michael, Hasida Ben-Zur
doaj +1 more source
Cultura de los Cuidados, 2012 Aims: Were centred in understanding and explaining the meaning of natural resources for those people living with AIDS, from the perspective of anthropology of care, at the same time to determine which are those resources and their effectiveness from the ...
Socorro Piñones Martínez +2 more
doaj +1 more source