Results 91 to 100 of about 7,518,803 (303)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Organizational Arrangements for Developing Long-Range Water Resources Plans for Georgia

open access: yes, 1989
Proceedings of the 1989 Georgia Water Resources Conference, May 16-17, 1989, Athens, Georgia.The Georgia Department of Natural Resources (DNR) has developed a state water plan, introduced by Governor Harris, which calls for the state to construct 12 ...
Hatcher, Kathryn J.
core   +1 more source

Couples’ Psychological Resources and Marital Satisfaction: The Mediating Role of Marital Support

open access: yesEurope's Journal of Psychology
The aim of this study was to assess the interdependent relations among psychological resources, marital support, and marital satisfaction in married couples from the perspective of both dyad members, using the Actor-Partner-Interdependence-Model (APIM ...
Keren Michael, Hasida Ben-Zur
doaj   +1 more source

Pullman Moscow Water Resources Committee Status Report

open access: yes, 1969
The report provides an update of the ground water supply in the Pullman Moscow basin, further development of the water resources of the basin, and the possible ...
Pullman Moscow Water Resources Committee
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Other title: Kansas Housing Resources Corporation press releases, 2015; Other title: Kansas Housing Resources Corporation news releases, 2013

open access: yes, 2015
March 2015; application/pdf; Annual cumulation of 2015 issuesKansas Housing Resources Corporation's Jennifer Sexson Accepts NASCSP ...
Kansas Housing Resources Corporation.
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Summary of a Report on Geothermal Water Resources in Arizona: Feasibility Study

open access: yes, 1977
Published in cooperation with Arizona Water Commission and Office of Arid Lands Studies, University of Arizona.INTRODUCTION: Arid lands will undoubtedly experience increased energy stresses in the near future because of increasing internal populations ...
Norton, Denis L.   +3 more
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

ON THE CALCULATION OF THE SUCCESS RATE IN MINING [PDF]

open access: yesAnnals of the University of Petrosani: Economics, 2013
Mankind has always relied on resources. The mineral resources represent an important part of the resources required by the society. But mining has its own specificities, not only from technical point of view, but from economic point of view, tool ...
RAREŞ MUNTEANU
doaj  

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