Results 91 to 100 of about 771,436 (267)

A rational system of the own resources for the European Community

open access: yesEconomics and Business Review, 2005
A system of EC own resources needs a comprehensive reform because it does not correspond with the new reality of enlarged European Union (EU). The system analysis according to the own resources criteria in federal country proves that the present system of EC resources neither guarantees EC financial autonomy nor equity in taxation between Member States
openaire   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Behind the sacred tree: local people and their natural resources sustain-ability

open access: yesReinwardtia, 2014
Local communities have their own means of maintaining their traditional know-ledge and sustaining the production system of natural resources by designating the resources as sacred.
Mohammad Royyani, Joeni Rahajoe
doaj  

Fostering Teachers’ Work Engagement: The Role of Emotional Self-Efficacy Toward One’s Own Emotions, Professional Self-Efficacy, and Job Resources

open access: yesEuropean Journal of Investigation in Health, Psychology and Education
The present cross-sectional study explored the synergic role of self-report measures of emotional self-efficacy toward one’s own emotions (i.e., the extent to which individuals perceive themselves as confident and effective in managing their emotions ...
Alessio Tesi   +4 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Developing LDers: a spotlight on resources and framework for the ALDinHE continuous professional development project

open access: yesJournal of Learning Development in Higher Education
How do learning developers (LDers), at all stages of their career, contribute to their own development, and that of LD colleagues? Our community is rich with knowledge, experience, innovation and creativity, with which it enhances the professional ...
Amy West, Samantha Thomas, Kate Coulson
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Successful ability to stay at home - an interview study exploring multiple diagnosed older persons and their relatives’ experiences

open access: yesBMC Geriatrics
Background Society places increased demands on regions and municipalities to jointly carry out activities for multi-diagnosed older persons with extensive coordination needs.
Lena-Karin Gustafsson   +3 more
doaj   +1 more source

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