Results 51 to 60 of about 771,436 (267)

The EU own resources system — Reform needs and options [PDF]

open access: yesIntereconomics, 2013
The most prominent and debated issues in the negotiations on the next Multiannual Financial Framework for the EU for the period 2014–2020 were the overall budget volume, the structure of expenditures and the continuation of the rebates for (some) net contributor countries.
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

In sickness and in health: The role of marital partners in cancer survival

open access: yesSSM: Population Health, 2017
Married cancer patients enjoy a survival advantage, potentially attributable to better health at diagnosis, earlier contact with health personnel, and/or access to resources to ensure more optimal treatment. These mechanisms only invoke the mere presence
Astri Syse, Torkild Hovde Lyngstad
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

MEASURES TO IMPROVE THE STRUCTURE OF EUROPEAN UNION EXPENDITURE [PDF]

open access: yesRisk in Contemporary Economy, 2015
In the current programming is proposed a reform of the own resources system, which involves removing the current own resources based on value added tax (VAT) and introducing two new own resources, one based on a portion of the proceeds gained from the ...
Cristina Voicu-Olteanu   +2 more
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

ASSESSMENT OF FINANCIAL PREREQUISITES FOR INNOVATION-ORIENTED DEVELOPMENT OF AN ENTERPRISE

open access: yesФінансово-кредитна діяльність: проблеми теорії та практики
The purpose of the article is to develop a public-reporting-based diagnostic approach for assessing how the structure of own financial resources is associated with the innovation-oriented development of a large agro-industrial and food enterprise.
Уляна Ніконенко   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy