Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Generosity as a Scientific Method: Building Knowledge and Community in a Competitive World. [PDF]
Andrade BB.
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Traditional Brewery (Atella) and Distillery (Brint) By-Products Utilisation Practices as Dairy Feed Source in Machakel District of East Gojjam, Amhara Region, Ethiopia. [PDF]
Mossie T +5 more
europepmc +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Digital Literacy Institutional Focus Group Resources
As part of the PriDE JISC Digital Literacy project a number of creative think-tanks (Faculty Learning Communities) were set up to consider digital literacy in the University of Bath.
Vic Jenkins - University of Bath
core
Supporting Health Care Professions Learners Experiencing Grief Using the TEARS Framework: A Workshop for Interprofessional Educators. [PDF]
Bloomhardt HM +4 more
europepmc +1 more source
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Balancing one's own life with caregiving for a sibling with schizophrenia: A qualitative study. [PDF]
Kawaguchi M +4 more
europepmc +1 more source

