Results 81 to 90 of about 7,254,380 (299)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Board structure, Ownership structure, and Firm performance : Evidence from Banking [PDF]

open access: yes
This paper examines the interrelations among five ownership and board characteristics in a sample of 260 bank and savings-and-loan holding companies. These governance characteristics, designed to reduce agency problems between shareholders and managers ...
Mohamed Belkhir
core  

Pengaruh Struktur Kepemilikan Saham dan Struktur Dewan Komisaris terhadap Kinerja Perusahaan

open access: yesJurnal Akuntansi Kontemporer, 2017
Shareholding structure and the structure of the board of commissioners that are the focus in this study were (1) the internal ownership structure (insider ownership), which share ownership by managers and commissioners, (2) stock ownership by ...
Cyrillius Martono   +1 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

INTERMEDIATION CHARACTERISTICS AND FUNCTIONS OF BANKING IN INDONESIA

open access: yesBuletin Ekonomi Moneter dan Perbankan, 2012
This paper analyzes the influence of ownership and specific characteristic of banks on the capital structure and the intermediation function of commercial banks in Indonesia. Using multivariate regression on bank level data of 2006-2009, the result shows
Renniwaty Siringoringo
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Corporate Ownership Structure and Firm Performance: Evidence from Greek Firms [PDF]

open access: yes
The Berle-Means thesis (1932) implies that diffuse ownership adversely affects firm performance. This paper tries to investigate whether there is strong evidence to support the notion that variations across firms in observed ownership structures result ...
Panayotis Kapopoulos, Sophia Lazaretou
core  

Board structure, ownership structure and firm performance: A study of New Zealand listed-firms [PDF]

open access: yes, 2012
This paper investigates the role of board structure and the effect of ownership structures on firm performance in New Zealand's listed firms. Several studies, the majority from the U.S., U.K.
Fauzi, Fitriya, Locke, Stuart
core   +1 more source

Ownership structure and capital structure dynamics in South African firms

open access: yesSouth African Journal of Economic and Management Sciences
Background: The ownership structure can impact capital structure decisions as owners are an influential group that govern the financial decisions of firms.
Delane Naidu
doaj   +1 more source

The Effect of Firm Size, Leverage, Profitability, Ownership Structure, and Firm Age on Enterprise Risk Management Disclosures

open access: yesAccounting Analysis Journal, 2020
This study aims to examine the effect of firm size, leverage, profitability, domestic institutional ownership structure, foreign ownership structure, local individual ownership structure, and firm age on enterprise risk management disclosure.
Choiru Rujiin, Sukirman Sukirman
doaj   +1 more source

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