Results 51 to 60 of about 7,735 (257)

Complexing in Unsymmetrical Electrolytes [PDF]

, 1970
The first and second dissociation constants of d-tartaric acid have been determined by means of pH studies with a glass electrode in 0.1, 0.2 and 0.4M tetramethylammonium chloride media at ...
Midgley, Derek
core  

Nonenzymatic Carboxylate Phosphorylation in Water

European Journal of Organic Chemistry, EarlyView.
The phosphorylation of carboxylic acids to acyl phosphates is a recurring reaction in the core of microbial metabolism, a set of processes thought to date back to the origins of life. This study shows that carboxylate phosphorylation occurs in water without enzymes or adenosine triphosphate (ATP), enabled by diamidophosphate and nitrite.
Weiqiang Chen, Joris Zimmermann, Jonas Dechent, Joseph Moran   +3 more
wiley   +1 more source

The beginnings of proto-metabolism at the origin of life in alkaline hydrothermal vents [PDF]

, 2018
The origin of life is still one of the most exciting scientific quests, one that has deep implications that go far beyond science itself. This thesis explores the possible origins of carbon and energy proto-metabolism in Hadean alkaline hydrothermal ...
Camprubi Casas, Eloi
core  

Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation

Nature Immunology, 2019
Pathogen-associated molecular patterns (PAMPs) have the capacity to couple inflammatory gene expression to changes in macrophage metabolism, both of which influence subsequent inflammatory activities. Similar to their microbial counterparts, several self-
M. di Gioia, R. Spreafico, James R. Springstead, M. Mendelson, R. Joehanes, D. Levy, I. Zanoni   +6 more
semanticscholar   +1 more source

Identification of the Yeast Mitochondrial Transporter for Oxaloacetate and Sulfate [PDF]

Journal of Biological Chemistry, 1999
Saccharomyces cerevisiae encodes 35 members of the mitochondrial carrier family, including the OAC protein. The transport specificities of some family members are known, but most are not. The function of the OAC has been revealed by overproduction in Escherichia coli, reconstitution into liposomes, and demonstration that the proteoliposomes transport ...
PALMIERI, Luigi, VOZZA, Angelo, AGRIMI, GENNARO, DE MARCO V., RUNSWICK M. J., PALMIERI F., WALKER J. E.   +6 more
openaire   +5 more sources

Single‐microbe RNA sequencing uncovers unexplored specialized metabolic functions of keystone species in the human gut

iMeta, EarlyView.
The human body is inhabited by trillions of microorganisms that play a crucial role in health and diseases. Although our understanding of the species and functional composition of the human gut microbiome is rapidly expanding, species–function heterogeneity and dynamic activities in human microecosystem niches remain unclear.
Yifei Shen, Wenxin Qu, Mengdi Song, Tianyu Zhang, Chang Liu, Xiaofeng Shi, Xinxin Xu, Jingjing Jiang, Liguo Ding, Fangyu Mo, Zheying Mao, Mingzhu Huang, Ziye Xu, Jiaye Chen, Enhui Shen, Jian Ruan, Jiong Liu, Michael P. Timko, Yu Chen, Longjiang Fan, Shufa Zheng, Yongcheng Wang   +21 more
wiley   +1 more source

A specific translocator for oxaloacetate transport in chloroplasts [PDF]

FEBS Letters, 1984
Evidence is provided that oxaloacetate is taken up by chloroplasts from maize and spinach leaves by a high‐affinity carrier. Apparent K m values for oxaloacetate are about 45 and 9 μM, respectively. Uptake was measured by following [4‐14C]oxaloacetate reduction in illuminated chloroplasts.
M.D. Hatch, U.I. Flügge, Hans W. Heldt, L. Dröscher   +3 more
openaire   +2 more sources

Synthetic biology for medical biomaterials

Interdisciplinary Medicine, EarlyView.
Synthetic biology platform has been utilized to produce a variety of medical biomaterials (MBMs), such as polylactic acid (PLA), polyhydroxyalkanoates (PHAs), hyaluronic acid (HA), collagen (COL), poly(β‐malic acid) (PMLA), poly‐γ‐glutamic acid (γ‐PGA), alginate (ALG), chitosan (CS), bacterial cellulose (BC), and antimicrobial peptides (AMPs).
Tao Xu, Xiao‐Yun Huang, Jin‐Wei Dao, Da Xiao, Dai‐Xu Wei   +4 more
wiley   +1 more source

Kalanchoë PPC1 Is Essential for Crassulacean Acid Metabolism and the Regulation of Core Circadian Clock and Guard Cell Signaling Genes[CC-BY]

The Plant Cell, 2020
Silencing phosphoenolpyruvate carboxylase in a Crassulacean acid metabolism species prevented nocturnal CO2 fixation and malate accumulation and perturbed the circadian clock and guard cell signaling.
Susanna F. Boxall, Nirja Kadu, L. Dever, Jana Kneřová, J. Waller, P. Gould, J. Hartwell   +6 more
semanticscholar   +1 more source

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source