Results 61 to 70 of about 7,735 (257)
Quantitative model for $^{13}$C tracing applied to citrate production and secretion of prostate epithelial tissue [PDF]
arXiv, 2019 Healthy human prostate epithelial cells have the unique ability to produce and secrete large amounts of citrate into the lumen of the prostate. Citrate is a Krebs cycle metabolite produced in the condensation reaction between acetyl-CoA and oxaloacetate in the mitochondria of the cell. With the application of $^{13}$C enriched substrates, such as $^{13}
arxiv
The application of a novel sampling device to the on-line analysis of fermentation broth [PDF]
, 1993 This thesis describes the development of an automated, aseptic, sampling, centrifugation and analysis system for fermentation broth, and its link to a process control system for the control of sugars and organic acids in fermentation processes ...
Turner, C.
core
Metabolism of Exogenous Oxaloacetate in Isolated Hepatocytes
Experimental Biology and Medicine, 1981 AbstractThe utilization of exogenous oxaloacetate (OAA) was studied in isolated rat liver parenchymal cells. Phenylpyruvate and α-cyanohydroxycinnamate, which inhibit pyruvate carboxylase (EC 6.4.1.1) and pyruvate transport across the mitochondrial membrane, respectively, were equally effective in decreasing glucose formation from pyruvate and OAA ...
Richard A. Freedland, Stephen B. Smith
openaire +3 more sources
Reduction of oxaloacetate by pig liver isocitrate dehydrogenase [PDF]
FEBS Letters, 1970 Pure isocitrate dehydrogenase from pig liver cytoplasm catalyses the reduction of oxaloacetate by NADPH at a rate comparable with that observed for the usual substrates. The products are NADP and D‐malate, the ‘unatural’ isomer. High concentrations of magnesium (25 mM) are necessary for maximal activity, and the reaction is not appreciably reversible ...
K.F. Tipton, J.A. Illingworth
openaire +3 more sources
Rapid and chemically diverse C transfer from trees to mycorrhizal fruit bodies in the forest
Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Ectomycorrhizal fungi (EMF) are common belowground tree symbionts, supplying trees with water and nutrients. In return, large amounts of C assimilated by trees can be allocated into EMF. However, the chemical forms in which the C is transferred from trees to fungi under
Alon Rapaport +4 more
wiley +1 more source
Insect Science, EarlyView.Distinct lineages of the grasshopper Chorthippus parallelus (Orthoptera: Acrididae) form a well‐known hybrid zone (HZ) in the Pyrenees mountain range; the Iberian endemism C. p. erythropus (Cpe) and the subspecies C. p. parallelus, (Cpp) widely distributed throughout the rest of Europe. Both subspecies differ in diverse traits, including the strains of
Patricia Jiménez‐Florido +4 more
wiley +1 more source
Nature Communications, 2019 How microbes dynamically coordinate uptake and simultaneous utilization of nutrients in complex nutritional ecosystems is still an open question. Here, we develop a constraint-based modeling approach that exploits non-targeted exo-metabolomics data to ...
M. Zampieri +4 more
semanticscholar +1 more source
Effects of Aging on Glucose and Lipid Metabolism in Mice
Aging Cell, Volume 24, Issue 4, April 2025.Lien et al. report a characterization of metabolism with aging across three different strains of mice. They find that glucose metabolism is robust during healthy aging; however, aging tissues exhibit evidence of upregulated fatty acid and sphingolipid metabolism reactions that regenerate NAD+ from NADH.
Evan C. Lien +8 more
wiley +1 more source
Longevity Humans Have Youthful Erythrocyte Function and Metabolic Signatures
Aging Cell, Volume 24, Issue 5, May 2025.Longevity humans have “a youthful erythrocyte function and metabolism” with a youth‐like oxygen release and anti‐oxidative capability to combat tissue hypoxia and improve healthspan. ABSTRACT Longevity individuals have lower susceptibility to chronic hypoxia, inflammation, oxidative stress, and aging‐related diseases.
Fang Yu +17 more
wiley +1 more source
Aging Cell, Volume 24, Issue 5, May 2025.Old people with or without sarcopenia exhibited different gut microbiota and metabolite compositions. Mice receiving microbes from people with sarcopenia displayed lower muscle mass and strength compared with those receiving microbes from non‐sarcopenic donors.
Chaoran Liu +14 more
wiley +1 more source