Results 71 to 80 of about 7,735 (257)

Diatom triacylglycerol metabolism: from carbon fixation to lipid droplet degradation

open access: yesBiological Reviews, EarlyView.
ABSTRACT Diatoms are a prominent microalgae family that has attracted interest for its production of molecules of biotechnological interest. Their fatty acid profile is rich in health‐beneficial omega‐3 eicosapentaenoic acid (EPA). Furthermore, under nutrient‐deprived conditions, many diatom species, notably Phaeodactylum tricornutum, Thalassiosira ...
Victor Murison   +3 more
wiley   +1 more source

Citrate--new functions for an old metabolite.

open access: yesBiological chemistry, 2014
Citrate is an important substrate in cellular energy metabolism. It is produced in the mitochondria and used in the Krebs cycle or released into cytoplasm through a specific mitochondrial carrier, CIC.
V. Iacobazzi, V. Infantino
semanticscholar   +1 more source

Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals

open access: yesCell Proliferation, EarlyView.
One‐third of the world's population is affected by metabolic syndrome. Complicated pathogenesis and limited drugs cause the growing prevalence of metabolic syndrome. Macrophage‐mediated metaflammation is closely associated with the development of metabolic syndrome. The role of phytochemicals targeting macrophages in the treatment of metabolic syndrome
Zeting Ye   +6 more
wiley   +1 more source

FAHD1 and mitochondrial metabolism: a decade of pioneering discoveries

open access: yesThe FEBS Journal, EarlyView.
This paper reviews a decade of research on FAHD1, an important yet underappreciated enzyme in mitochondrial metabolism. FAHD1 plays a crucial role in energy production, oxidative stress regulation, and processes related to aging and overall health.
Elia Cappuccio   +9 more
wiley   +1 more source

Inhibition of Hypoxia-inducible Factor (HIF) Hydroxylases by Citric Acid Cycle Intermediates

open access: yesJournal of Biological Chemistry, 2007
The stability and transcriptional activity of the hypoxia-inducible factors (HIFs) are regulated by two oxygen-dependent events that are catalyzed by three HIF prolyl 4-hydroxylases (HIF-P4Hs) and one HIF asparaginyl hydroxylase (FIH).
P. Koivunen   +5 more
semanticscholar   +1 more source

Protein import into bacterial endosymbionts and evolving organelles

open access: yesThe FEBS Journal, EarlyView.
The acquisition of bacterial endosymbionts by ancient host cells followed by massive adaptation of the partners gave rise to mitochondria and plastids. Today, various systems with younger and less integrated endosymbionts provide insights into the initial steps in the endosymbiont to organelle transition.
Megan E. S. Sørensen   +3 more
wiley   +1 more source

A non-canonical tricarboxylic acid cycle underlies cellular identity

open access: yesNature, 2022
Paige K. Arnold   +10 more
semanticscholar   +1 more source

Succinate receptor 1 signaling mutually depends on subcellular localization and cellular metabolism

open access: yesThe FEBS Journal, Volume 292, Issue 8, Page 2017-2050, April 2025.
SUCNR1, activated by succinate, is a Gi‐ and Gq‐coupled receptor present at the plasma membrane and in endosomes. There are conflicting reports about the pro‐/anti‐inflammatory effects of the succinate‐SUCNR1 signaling axis, and these are likely due to localization‐dependent signaling.
Aenne‐Dorothea Liebing   +11 more
wiley   +1 more source

Effect of Dietary Supplementation of Organic Acids on Performance, Intestinal Histomorphology, and Serum Biochemistry of Broiler Chicken

open access: yesVeterinary Medicine International, 2010
The aim of the study was to determine the effect of dietary supplementation of organic acids on the performance, intestinal histomorphology, and blood biochemistry of broiler chicken. The birds in the control (T1) group were fed the basal diet whereas in
S. Adil   +4 more
semanticscholar   +1 more source

Oxaloacetate: A novel neuroprotective for acute ischemic stroke

open access: yesThe International Journal of Biochemistry & Cell Biology, 2012
It is well established that glutamate acts as an important mediator of neuronal degeneration during cerebral ischemia. Different kind of glutamate antagonists have been used to reduce the deleterious effects of glutamate. However, their preclinical success failed to translate into practical treatments.
Pedro Ramos-Cabrer   +3 more
openaire   +4 more sources

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