Results 81 to 90 of about 7,735 (257)

Protein succinylome analysis identifies citrate synthase as a central regulator of osteoclast metabolic activity

open access: yesThe FEBS Journal, EarlyView.
RANKL treatment induces expression of the aconitate decarboxylase (ACOD1) in differentiating osteoclasts, which increases succinate levels. The initially high expression of ACOD1 decreases towards the end of differentiation when the levels of the desuccinylase SIRT5 increase. Succinylation of citrate synthase (CS) was detected exclusively in stimulated
Dayoung Yu   +7 more
wiley   +1 more source

Probing the Metabolic Network in Bloodstream-Form Trypanosoma brucei Using Untargeted Metabolomics with Stable Isotope Labelled Glucose

open access: yesPLoS Pathogens, 2015
Metabolomics coupled with heavy-atom isotope-labelled glucose has been used to probe the metabolic pathways active in cultured bloodstream form trypomastigotes of Trypanosoma brucei, a parasite responsible for human African trypanosomiasis.
Darren J. Creek   +16 more
semanticscholar   +1 more source

Comparative proteomics analysis of root and nodule mitochondria of soybean

open access: yesPlant, Cell &Environment, EarlyView.
Abstract Legumes perform symbiotic nitrogen fixation through rhizobial bacteroids housed in specialised root nodules. The biochemical process is energy‐intensive and consumes a huge carbon source to generate sufficient reducing power. To maintain the symbiosis, malate is supplied by legume nodules to bacteroids as their major carbon and energy source ...
Wai‐Ching Sin   +4 more
wiley   +1 more source

Concurrent Measurement of O2 Production and Isoprene Emission During Photosynthesis: Pros, Cons and Metabolic Implications of Responses to Light, CO2 and Temperature

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Traditional leaf gas exchange experiments have focused on net CO2 exchange (Anet). Here, using California poplar (Populus trichocarpa), we coupled measurements of net oxygen production (NOP), isoprene emissions and δ18O in O2 to traditional CO2/H2O gas exchange with chlorophyll fluorescence, and measured light, CO2 and temperature response ...
Kolby Jeremiah Jardine   +8 more
wiley   +1 more source

Thermodynamic constraints on the citric acid cycle and related reactions in ocean world interiors [PDF]

open access: yesarXiv
Icy ocean worlds attract significant interest for their astrobiological potential due to subsurface oceans, organics, and chemical energy sources. We quantify thermodynamic viability of metabolism-relevant reactions at pressure-temperature conditions of Enceladus, Europa, Titan, Ganymede, and the Lost City Hydrothermal Field for comparison.
arxiv  

Contextualized Metabolic Modelling Revealed Factors Affecting Isoflavone Accumulation in Soybean Seeds

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Isoflavones, secondary metabolites with numerous health benefits, are predominantly found in legume seeds, especially soybean; however, their contents in domesticated soybean seeds are highly variable. Wild soybeans are known for higher seed isoflavone contents than cultivars. Here we used experimental and modelling approaches on wild soybean (
Carolina A. Contador   +5 more
wiley   +1 more source

Coupling mechanism of the oxaloacetate decarboxylase Na+ pump

open access: yesBiochimica et Biophysica Acta (BBA) - Bioenergetics, 2001
The oxaloacetate decarboxylase Na(+) pump consists of subunits alpha, beta and gamma, and contains biotin as the prosthetic group. The peripheral alpha subunit catalyzes the carboxyltransfer from oxaloacetate to the prosthetic biotin group to yield the carboxybiotin enzyme.
Markus Schmid   +2 more
openaire   +3 more sources

Evolutionary Conserved and Divergent Responses to Copper Zinc Superoxide Dismutase Inhibition in Plants

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT After an initial evolution in a reducing environment, life got successively challenged by reactive oxygen species (ROS), especially during the great oxidation event (GOE) that followed the development of photosynthesis. Therefore, ROS are deeply intertwined into the physiological, morphological and transcriptional responses of most present‐day
Stephanie Frohn   +12 more
wiley   +1 more source

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