Results 51 to 60 of about 2,492 (186)

Structural‐to‐Functional Complexity Transformations Enabled by Bridged Polyheterocycles: Access to Cis‐1,3‐Diamines and Amino‐Alcohols

ChemistryEurope, Volume 4, Issue 6, June 2026.
Polycyclic intermediates enable stereocontrolled synthesis of densely functionalized cis‐1,3‐diamine and amino alcohol carbocycles and heterocycles via structural‐to‐functional complexity transformations from low‐complexity starting material. Cis‐1,3‐functionalized carbocycles and saturated heterocycles are ubiquitous motifs in natural products ...
Jiayi Zhu, Erica Benedetti, Laurent Micouin   +2 more
wiley   +1 more source

Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application

European Journal of Organic Chemistry, Volume 29, Issue 19, 22 May 2026.
Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley   +1 more source

Accessing New Phenanthroline–Oxazine Scaffolds as Copper‐Dependent DNA Damaging Probes

ChemBioChem, Volume 27, Issue 8, April 2026.
New phenanthroline–oxazine ligands derived from natural amino acids are synthesized through an optimized, predictive strategy. When coordinated to copper, these scaffolds display tunable DNA binding, groove selectivity, and oxidative cleavage activity, revealing clear structure activity relationships and expanding the toolbox of copper‐dependent ...
Rebecca Lynn, Alex Gibney, Eva Delahunt, Stephen MacDonald‐Brown, Carlos Lence, Miles Kenny, Matt Allen, Ravil Khaybullin, Iva Lukac, Andrew Jordan, Andrew Kellett   +10 more
wiley   +1 more source

Synthesis of Substituted Pyrido-oxazine through Tandem SN2 and SNAr Reaction

SynOpen, 2018
Pyrido-oxazine derivatives have been synthesized by employing tandem SN2 and SNAr reaction between 2,4,6-tribromo-3-(2-bromoethoxy)pyridine or 2,4,6-tribromo-3-(3-bromopropoxy)pyridine and a variety of primary amines. Moderate to good regioselectivity in
Mosim Amin Pathan, Faiz Ahmed Khan
doaj   +1 more source

The Impact of Chemical Modifications on the Photochromism of Spiropyran: A Roadmap to Navigate Powerful Photochromes

ChemPhotoChem, Volume 10, Issue 4, April 2026.
This review summarizes how even minor chemical modifications can be used to shape spiropyran photochromism. We highlight how substituents, strain, and heteroatoms tune absorption, stability, switching efficiency, and overall photochromic behaviour.
Gianni Pacella, Giuseppe Portale
wiley   +1 more source

Bio-computational modeling, POM analysis and molecular dynamic simulation for novel synthetic quinolone and benzo[d][1,3]oxazine candidates as antimicrobial inhibitors. [PDF]

Sci Rep
The current study offers a metal-free, direct, and successful synthesis technique for a new series of quinolinone and benzo[d][1,3]oxazine, along with an assessment of their biological activities.
Elsayed DA, Abdu ME, Marzouk MA, Mahmoud EM, El-Shwiniy WH, Spring AM, Shehab WS.   +6 more
europepmc   +2 more sources

Multi‐Scale Structural Insights Into Amphiphilic Model PEG–PCL Co‐Networks From LS and SANS

Macromolecular Chemistry and Physics, Volume 227, Issue 7, 14 April 2026.
We present a multiscale structural study of amphiphilic PEG–PCL co‐networks combining light scattering in THF and small‐angle neutron scattering in D2O. This dual‐solvent approach reveals how solvent quality, polymer volume fraction, and PEG/PCL interactions govern static and dynamic correlation lengths, network homogeneity, and nanoscale domain ...
Sebastian Seitel, Nora Fribiczer, Brian Carrick, Stephanie Ihmann, Frank Böhme, Bradley D. Olsen, Sebastian Seiffert   +6 more
wiley   +1 more source

Amphiphilic Polymer Model Networks Synthesized by Different Hetero‐Complementary Coupling Reactions of Tetra‐PEG and Tetra‐PCL Stars

Macromolecular Chemistry and Physics, Volume 227, Issue 7, 14 April 2026.
Amphiphilic co‐networks (ACN) synthesized by different hetero‐complementary reactions of hydrophilic tetra‐PEG and hydrophobic tetra‐PCL stars are compared. For the ACNs, equilibrium volume swelling degrees (Qv) are determined. Information about the ACNs micro structure (connectivity distribution) is obtained from proton low‐resolution multiple‐quantum
Stephanie Ihmann, Bidit Lamsal, Martin Geisler, Kay Saalwächter, Frank Böhme   +4 more
wiley   +1 more source

Comparison of Blood Cell Count Results Between MgSO4 and K2EDTA. Stability and Accuracy of Platelet Counting With MgSO4

International Journal of Laboratory Hematology, Volume 48, Issue 2, Page 336-344, April 2026.
ABSTRACT Introduction We investigated the stability and accuracy of platelets with MgSO4 and compared the results of blood counts between MgSO4 and K2EDTA. Methods Platelet stability as a function of time was assessed on the XN Sysmex analyzer by comparing the percentage deviation to the desirable bias of the EFLM.
Michel Soulard, Hela Ketatni, Pascale Croix, Soraya Wuilleme, Patrick Cohen   +4 more
wiley   +1 more source

Microwave-assisted one-pot efficient synthesis of functionalized 2-oxo-2-phenylethylidenes-linked 2-oxo-benzo[1,4]oxazines and 2-oxo-quino[1,4]oxalines: Synthetic Applications, Antioxidant activity, SAR and Cytotoxic Studies

Acta Chimica Slovenica, 2017
A microwave-assisted, environmentally benign green protocol for the synthesis of functionalized (Z)-3-(2-oxo-2-phenylethylidene)-3, 4-dihydro-2H-benzo[b][1,4]oxazin-2-ones 11a-n in excellent yields (upto 97%) and (Z)-3-(2-oxo-2-phenylethylidene)-3,4 ...
Vashundhra Sharma, Pradeep K. Jaiswal, Dharmendra K. Yadav, Mukesh Saran, Jaroslav Prikhodko, Manas Mathur, Ajit K. Swami, Irina V. Mashevskaya, Sandeep Chaudhary   +8 more
doaj   +1 more source