Results 171 to 180 of about 1,172,237 (299)

Reversible Enzymatic Switching of the Oxidation State of a Eu^III/II Complex Controls Relaxivity. [PDF]

J Am Chem Soc
Sarson ET, Cooper SM, Sedgwick AC, Berger AG, Twigger SA, Hammond EM, Vincent KA, Faulkner S.   +7 more
europepmc   +1 more source

Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth, Mert Sisman, Jinwei Zhang, Hyeong‐geol Shin, Xu Li, Bela Turk, Ali Fatemi, Thanh Nguyen, Eric Mallack   +8 more
wiley   +1 more source

Steering Pt Cluster Dimensionality via the Surface Oxidation State of CeO₂(111) Thin Films. [PDF]

ACS Catal
Reich J, Soltanmohammadi M, Vonk V, Kaiser S, Heiz U, Stierle A, Esch F, Lechner BAJ.   +7 more
europepmc   +1 more source

The Highest Oxidation State of Rhodium: Rhodium(VII) in [RhO₃ ]. [PDF]

Angew Chem Int Ed Engl, 2022
da Silva Santos M, Stüker T, Flach M, Ablyasova OS, Timm M, von Issendorff B, Hirsch K, Zamudio-Bayer V, Riedel S, Lau JT.   +9 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Low-oxidation state dirhodium complex produced by four-electron reduction of dirhodium(ii) complex supported by a flexible macrocyclic ligand. [PDF]

Chem Sci
Yan L, Moriyama T, Akita Y, Muratsugu S, Tada M, Yamashita M, Morimoto Y.   +6 more
europepmc   +1 more source

Stability of Coumarins and Determination of the Net Iron Oxidation State of Iron-Coumarin Complexes: Implications for Examining Plant Iron Acquisition Mechanisms. [PDF]

ACS Earth Space Chem, 2023
Kang K, Schenkeveld WDC, Weber G, Kraemer SM.   +3 more
europepmc   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Covalent Bonding Between Ir and High-Oxidation State Sb Constrained by Quinoline Scaffolds. [PDF]

Inorg Chem
Kong F, Webber CK, Kumawat J, Quirion KP, Ou X, Dickie DA, Ess DH, Gunnoe TB.   +7 more
europepmc   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source