Results 71 to 80 of about 13,910,228 (354)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

First-principles investigation of the effect of Co in stabilizing the structures of layer-structured cathodes in delithiated state

Materials Research Express, 2020
The structural and chemical features of delithiated layer-structured cathodes (Li _0.333 TMO _2 , TM = Ni and Co) are investigated. Energetically stable structures are evaluated by combing particle swarm optimization algorithm and density functional ...
Yongseon Kim
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Impact of exercise-nutritional state interactions in patients with type 2 diabetes

, 2020
Introduction This study examines the role of nutritional status during exercise training in patients with type 2 diabetes mellitus by investigating the effect of endurance-type exercise training in the fasted versus the fed state on clinical outcome ...
Calders, Patrick, Celie, Bert, Dendale, Paul, Hansen, Dominique, Lapauw, Bruno, Stevens, An, van Loon, Luc JC, Vandenabeele, Frank, Verboven, Kenneth, Wens, Inez   +9 more
core   +1 more source

Correlation Between Reactivity and Oxidation State of Cobalt Oxide Catalysts for CO Preferential Oxidation

ACS Catalysis, 2019
Catalytic performance is known to be influenced by several factors, with the catalyst surface oxidation state being the most prominent of all. However, in the great majority of industrial heterogeneous catalytic reactions the oxidation state of the ...
L. Zhong, T. Kropp, W. Baaziz, O. Ersen, D. Teschner, R. Schlögl, M. Mavrikakis, S. Zafeiratos   +7 more
semanticscholar   +1 more source

Engineering High-Spin State Cobalt Cations in Spinel Zinc Cobalt Oxide for Spin Channel Propagation and Active Site Enhancement in Water Oxidation.

Angewandte Chemie, 2021
Promoting the initially deficient but cost-effective catalysts to high-performing competitors is of significance in developing better catalysts. Spinel zinc cobalt oxide (ZnCo 2 O 4 ) is not considered as a superior catalyst for the electrochemical ...
Yuanmiao Sun, Xiao Ren, Shengnan Sun, Zheng Liu, S. Xi, Zhichuan J. Xu   +5 more
semanticscholar   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Inverse ceria-nickel catalyst for enhanced C–O bond hydrogenolysis of biomass and polyether

Nature Communications
Regulating interfacial electronic structure of oxide-metal composite catalyst for the selective transformation of biomass or plastic waste into high-value chemicals through specific C–O bond scission is still challenging due to the presence of multiple ...
Zelun Zhao, Guang Gao, Yongjie Xi, Jia Wang, Peng Sun, Qi Liu, Chengyang Li, Zhiwei Huang, Fuwei Li   +8 more
doaj   +1 more source

Unraveling the Effects of Melt–Mantle Interactions on the Gold Fertility of Magmas

Frontiers in Earth Science, 2020
The oxidation state of the Earth’s mantle and its partial melting products exert a key control on the behavior and distribution of sulfur and chalcophile and siderophile elements between the mantle and crust, underpinning models of ore deposit formation.
Santiago Tassara, Santiago Tassara, Santiago Tassara, Martin Reich, Martin Reich, Brian A. Konecke, Brian A. Konecke, José María González-Jiménez, Adam C. Simon, Diego Morata, Diego Morata, Fernando Barra, Fernando Barra, Adrian Fiege, Manuel E. Schilling, Alexandre Corgne   +15 more
doaj   +1 more source

Influence of Environment on Creep Properties of MC2 Single Crystal Superalloy at 1150°C [PDF]

, 2004
In order to reveal the effect of oxidation on thin blade walls, a new machine allowing tests up to 1250°C under controlled atmosphere has been designed.
Andrieu, Eric, Crabos, Fabrice, Dryepondt, Sébastien, Monceau, Daniel, Vernault, Cyril   +4 more
core   +1 more source