Results 61 to 70 of about 49,564 (298)

Wounding triggers MIRO-1 dependent mitochondrial fragmentation that accelerates epidermal wound closure through oxidative signaling. [PDF]

, 2020
Organisms respond to tissue damage through the upregulation of protective responses which restore tissue structure and metabolic function. Mitochondria are key sources of intracellular oxidative metabolic signals that maintain cellular homeostasis.
Chisholm, Andrew D, Fu, Hongying, Meng, Xinan, Xu, Jingxiu, Xu, Suhong, Yu, Xinghai, Zhao, Jianzhi, Zhou, Hengda, Zhou, Jinghua, Zhou, Yu   +9 more
core  

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

Willow Lignin Oxidation and Depolymerization under Low Cost Ionic Liquid

ACS Sustainable Chemistry & Engineering, 2016
Willow biomass was subjected to different pretreatmentconditions with triethylammonium hydrogen sulfate as solvent, andthe produced lignin solutions were treated by oxidation either homo-geneously using H2O2as oxidant or by heterogeneous catalysis usingTiO2. Lignin, residual lignin, oil, and the recovered ionic liquid (IL)were characterized in order to
Prado, R, Erdocia, X, De Gregorio, GF, Labidi, J, Welton, T   +4 more
openaire   +4 more sources

Chitosan copolymers for intranasal delivery of insulin: synthesis, characterization and biological properties [PDF]

, 2004
Recently, chitosan has been extensively investigated as a promising carrier in the field of drug delivery. To overcome its poor solubility at physiological pH and the cytotoxicity of trimethyl chitosan, PEGylated trimethyl chitosan copolymers were ...
Kissel, Thomas (Prof.), Mao, Shirui
core   +1 more source

Degradable Donor‐Acceptor Polymeric Mixed Ionic‐Electronic Conductors for Transient Electronics

Advanced Materials Technologies, EarlyView.
Here, we report degradable donor–acceptor (D–A) polymeric mixed ionic‐electronic conductors for transient electronics. We take a systematic side chain engineering approach to elucidate how molecular‐level modifications of donor–acceptor (D–A) polymer structures can satisfy demands that are often conflicting: degradability, charge carrier transport, and
Angela Lin, Zhichang Liu, Saroj Upreti, Stanley Lo, Nathan Sung Yuan Hsu, Xiaodan Gu, Sihong Wang, Helen Tran   +7 more
wiley   +1 more source

Sugar and chromosome stability: Clastogenic effects of sugars in vitamin B6-deficient cells [PDF]

, 2014
Pyridoxal 5'-phosphate (PLP), the active form of vitamin B6, has been implicated in preventing human pathologies, such as diabetes and cancer. However, the mechanisms underlying the beneficial effects of PLP are still unclear. Using Drosophila as a model
Gatti, Maurizio, Marzio, Antonio, Merigliano, Chiara, Verni', Fiammetta   +3 more
core   +3 more sources

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Novel biological approaches for the removal of chlorophenolics [AOX] from bleach plant effluent [PDF]

, 2005
No abstract ...
Veeramani, Harish
core  

cis-acting sequences and trans-acting factors in the localization of mRNA for mitochondrial ribosomal proteins [PDF]

, 2008
mRNA localization is a conserved post-transcriptional process crucial for a variety of systems. Although several mechanisms have been identified, emerging evidence suggests that most transcripts reach the protein functional site by moving along ...
AMORESANO, ANGELA, C. Cirulli, PIETROPAOLO, CONCETTA, PUCCI, PIETRO, RUSSO, ANNAPINA, RUSSO, GIULIA   +5 more
core   +1 more source

Cellular Snowballing: Cell Adhesion and Migration Drive the Self‐Assembly of Cell‐Microgel Biohybrid Spheroids

Advanced Science, EarlyView.
A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie, Sina Kheirabadi, Changhao Li, Aneesh Risbud, Aswathy Sebastian, Istvan Albert, Sulin Zhang, Amir Sheikhi   +7 more
wiley   +1 more source