Results 321 to 330 of about 522,162 (364)

Identification of CD38high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

Advanced Science, EarlyView.
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua, Limin Kong, Li Fan, Yanan Bai, Yujun Zhou, Yanfang Zhang, Qingwei Zhao, Xiaoyang Lu, Hongyu Yang, Hangyang Li, Peili Ding, Yuyu Nan, Qinghua Ji, Ping Yang, Lu Li, Yijing Xin, Lijuan Zhao, Wei Yang, Wenqiao Yu, Saiping Jiang   +19 more
wiley   +1 more source

An updated inventory of genes essential for oxidative phosphorylation identifies a mitochondrial origin in familial Ménière’s disease

Harhai M, Foged MM, Recazens E, Lisci M, Chollet S, Landoni JC, Laban N, Manley S, Lopez-Escamez JA, Lysakowski A, Jourdain AA.   +10 more
europepmc   +1 more source

COA6 promotes the oncogenesis and progression of breast cancer by oxidative phosphorylation pathway. [PDF]

J Cancer
Jin X, Chen X, Yu H, Liu Y, Lu X, Yin H, Dai W.   +6 more
europepmc   +1 more source

Restoration of defective oxidative phosphorylation to a subset of neurons prevents mitochondrial encephalopathy. [PDF]

EMBO Mol Med
Walker BR, Theard LM, Pinto M, Rodriguez-Silva M, Bacman SR, Moraes CT.   +5 more
europepmc   +1 more source

AHR signaling pathway mediates mitochondrial oxidative phosphorylation which leads to cytarabine resistance. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Jia Y, Li X, Chen L, Li L, Zhang S, Huang W, Zhang H.   +6 more
europepmc   +1 more source

Negative Selection in <i>Oreochromis niloticus</i> × <i>O. aureus</i> Hybrids Indicates Incompatible Oxidative Phosphorylation (OXPHOS) Proteins. [PDF]

Int J Mol Sci
Shirak A, Curzon AY, Seroussi E, Gershoni M.   +3 more
europepmc   +1 more source

Oxidative phosphorylation related gene COA6 is a novel indicator for the prognosis and immune response in lung adenocarcinoma. [PDF]

Sci Rep
Liu W, Jiang Y, Li G, Huang D, Qin T.
europepmc   +1 more source

Human neural stem cell-derived artificial organelles to improve oxidative phosphorylation. [PDF]

Nat Commun
Wang J, Zhao M, Wang M, Fu D, Kang L, Xu Y, Shen L, Jin S, Wang L, Liu J.   +9 more
europepmc   +1 more source

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Mechanism of Oxidative Phosphorylation

Nature, 1958
THE phenothiazine tranquillizer chlorpromazine has the following actions: (1) It inhibits electron transport between reduced diphosphopyridine nucleotide and cytochrome c in appropriate systems; the efficiency of the coupled phosphorylation is not affected. (2) Chlorpromazine is not effective in mitochondria treated with water or in non-phosphorylating
J. D. Judah, J. D. Judah, K. R. Rees, K. R. Rees, M. J. R. Dawkins, M. J. R. Dawkins   +5 more
openaire   +3 more sources

Efficiency of Oxidative Phosphorylation

Nature, 1954
THE quantitative yield of phosphate fixed during cellular oxidations deserves critical investigation, for it determines the efficiency with which utilizable energy may be derived from assimilated foodstuffs and it may influence metabolic regulatory mechanisms1. This problem has been the subject of many investigations (cf. Krebs et al.
J. H. Copenhaver, Henry A. Lardy
openaire   +3 more sources