Results 151 to 160 of about 4,045,081 (310)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Inactivation of PYR/PYL/RCAR ABA receptors by tyrosine nitration may enable rapid inhibition of ABA signaling by nitric oxide in plants

, 2015
Mari‐Cruz Castillo, Jorge Lozano‐Juste, Miguel González‐Guzmán, Lesia Rodríguez, Pedro L. Rodrı́guez, José León   +5 more
openalex   +2 more sources

Effect of pre-calving body condition score and previous lactation on BCS change, blood metabolites, oxidative stress and milk production in Holstein dairy cows [PDF]

, 2017
Negin Jamali Emam Gheise, Ahmad Riasi, Ahmad Zare Shahneh, Pietro Celi, S.M. Ghoreishi   +4 more
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Memory Manufacture Under Microgravity (MMuM): In‐Space Manufactured ZnO‐Based Resistive Random Access Memory for Emerging Computing Application

Advanced Electronic Materials
Resistive random access memory (RRAM) has attracted industrial and academic interests in emulating biological synapse features for neuromorphic computing for its flexibility and feasibility of analog behaviors.
Yujian Huang, Liangkui Jiang, Matthew Marander, Sai Prakash Maddineni, Hantang Qin, Shan Jiang, Curtis W. Hill, Myeong‐Lok Seol, Ying‐Chen Daphne Chen   +8 more
doaj   +1 more source

Influence of the dietary polyunsaturation level on chicken meat quality: lipid oxidation

, 2005
L. Cortinas, A.C. Barroeta, Cecilia Villaverde, Jaume Galobart, Francesc Guardiola, M.D. Baucells   +5 more
openalex   +1 more source

Anticonvulsant Activity of Essential Oil From Leaves of Zhumeria majdae (Rech.) in Mice: The Role of GABA_A Neurotransmission and the Nitric Oxide Pathway [PDF]

, 2020
Helia Aghamiri, Hamed Shafaroodi, Jinous Asgarpanah   +2 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

VOC ternary mixture effect on ppb level photocatalytic oxidation: Removal kinetic, reaction intermediates and mineralization

, 2017
O. Debono, Valérie Hequet, Laurence Le Coq, Nadine Locoge, Frédéric Thévenet   +4 more
openalex   +2 more sources