Results 151 to 160 of about 2,514,368 (260)

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source

Profiling the effect of low frequency mechanical vibration on the metabolic and oxidative stress responses of A431 carcinoma

FEBS Open Bio, EarlyView.
20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti, Chikahiro Imashiro, Takashi Morikura, Shogo Miyata, Akira Funahashi, Kenjiro Takemura   +5 more
wiley   +1 more source

Structural properties of transparent Ti-V oxide semiconductor thin films

Open Physics, 2013
Sieradzka Karolina, Kaczmarek Danuta, Morgiel Jerzy, Domaradzki Jaroslaw, Prociow Eugeniusz, Adamiak Bogdan   +5 more
doaj   +1 more source

Effect of particle oxidation, size and material on deformation, bonding and deposition during cold spray: a peridynamic investigation [PDF]

arXiv
Cold spray (CS) has emerged as an important additive manufacturing technology over the past decade. This study investigates the effect of oxide layers on the CS process, focusing on the deformation behavior of copper (Cu) and iron (Fe) particles upon collision with a matching substrate.
arxiv  

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

Aging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

Surface dose analysis and dosimetric comparison of Halcyon versus Truebeam in breast cancer radiotherapy: An OSL dosimetry study

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Breast cancer is a neoplastic disease with high prevalence among women. Radiotherapy is one of the principal treatment modalities for this disease, but it poses significant challenges. This study aimed to compare and evaluate the technical and dosimetric performance of conventional C‐arm linac systems and a new design, Halcyon, in the ...
Mustafa Çağlar, Kudret Akçay, Esra Serin, Dursun Eşitmez, Mehmet Sıddık Cebe, Navid Kheradmand, Ömer Yazıcı, Dilek Ünal, Evrim Metcalfe   +8 more
wiley   +1 more source

Clinical validation of myOSLchip: A beryllium oxide optically stimulated luminescent dosimeter (OSLD) system in radiotherapy dosimetry

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract In radiation oncology, inter‐fractional dosimetry using optically stimulated luminescent detectors (OSLDs) ensures accurate plan delivery and patient safety. RadPro International GmbH's myOLSchip system, featuring a beryllium oxide (BeO) OSL dosimeter, reader, and eraser, was characterized and calibrated with a Varian Truebeam for in‐vivo ...
Heath Davis, Jeffrey V. Siebers, Krishni Wijesooriya, Matt Mistro   +3 more
wiley   +1 more source

AAPM Task Group No. 249.B—Essentials and guidelines for clinical medical physics residency training program

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract The establishment of guidelines and curriculum standards for medical physics residency training is a critical component of setting expectations and competencies for the profession. Since the last publication of these standards, residency training has become integrated into the eligibility criteria for most medical physics certification bodies.
Jonathon A. Nye, Joseph P. Dugas, William D. Erwin, David P. Gierga, Darryl G. Kaurin, Stephanie M. Leon, Ho‐Ling Anthony Liu, Zheng Feng Lu, Alphonso W. Magri, Lynn N. Rill, Leah K. Schubert, Beth A. Schueler, Irina Vergalasova, John Vetter, Brian D. Wichman, Amy Shu‐Jung Yu, Dandan Zheng   +16 more
wiley   +1 more source