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Assessment of Susceptibility of Low-Density Lipoprotein to Oxidation
2003It is now recognized that oxidation of low-density lipoprotein (LDL) is a key event in the development of atherosclerosis (1). In vivo, oxidation is believed to occur primarily in the arterial wall. In early atherosclerotic lesions oxidation may be initiated by enzymes, including myeloperoxidase and 15-lipoxygenase, or by reactive nitrogen species ...
J, McEneny, I S, Young
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Physiological aspects of low-density lipoprotein oxidation
Current Opinion in Lipidology, 2000The oxidation of LDL is thought to be a major contributor to the development of atherosclerosis. Considerable descriptive evidence has been accumulated showing that oxidized LDL promotes pro-atherogenic events. However, direct evidence that oxidized LDL causes atherosclerosis is lacking.
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Is oxidized low‐density lipoprotein present in vivo?
Current Opinion in Lipidology, 1998Basic research has provided strong evidence that oxidation of LDL plays an important role in the pathogenesis of atherosclerosis. Several mechanisms have been identified which can lead to LDL oxidation in vivo. Clinical and epidemiological studies have provided circumstantial evidence that oxidized LDL, as measured by serum autoantibody levels, may be ...
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Physical changes of low-density lipoprotein on oxidation
Chemistry and Physics of Lipids, 1993Human LDL samples from different individuals were oxidized in three different ways. All oxidized LDL samples exhibited lower temperature of the thermotropic transition and lower content of the helical fraction of apoprotein B than the related native LDL. The observed decrease of the thermotropic transition temperature was up to 2 degrees C.
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OXIDIZED LOW DENSITY LIPOPROTEIN
Journal of Hypertension, 2000J. Jankowski +4 more
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OXIDATIVE MODIFICATION OF LOW DENSITY LIPOPROTEIN
Free Radical Biology and Medicine, 1990openaire +1 more source

