Results 101 to 110 of about 1,706 (114)

Environmental noise-induced changes to the IC-SNc circuit promotes motor deficits and neuronal vulnerability in a mouse model of Parkinson's Disease. [PDF]

PLoS Biol
Cui C, Yao Y, Shi Y, Lei J, Ren K, Wan K, Li T, Luo G, Xu Q, Li M, Peng X, Yang X, Yang J, Du J, Chen S, Tian B, Zhang P.   +16 more
europepmc   +1 more source

Les propriétés neuroprotectrices et autophagiques de l'oleuropéine sur des neurones dopaminergiques soumis à un stress oxydatif [PDF]

, 2015
Achour, Imène
core  

Genome-wide association study -Driven drug repositioning for the treatment of insomnia. [PDF]

J Genet Eng Biotechnol
Satria RD, Adikusuma W, Sukorini U, Avitasari DE, Kusuma Harahap IS, Setia Lesmana MH, Irham LM, Fatimah Harahap NI, Rinastiti P, Wardhana DA, Prabasaktya RW, Lin CF, Paramitasari A, Kusumadewi AF.   +13 more
europepmc   +1 more source

Transient Increases in Neural Oscillations and Motor Deficits in a Mouse Model of Parkinson's Disease. [PDF]

Int J Mol Sci
Wu Y, Lu L, Qing T, Shi S, Fang G.
europepmc   +1 more source

Machine learning approaches to detect hepatocyte chromatin alterations from iron oxide nanoparticle exposure. [PDF]

Sci Rep
Paunovic Pantic J, Vucevic D, Radosavljevic T, Corridon PR, Valjarevic S, Cumic J, Bojic L, Pantic I.   +7 more
europepmc   +1 more source

Ergothioneine Prevents Neuronal Cell Death Caused by the Neurotoxin 6-Hydroxydopamine. [PDF]

Cells
Yuzawa S, Nakashio M, Ichimura S, Shimoda M, Nakashima A, Marukawa-Hashimoto Y, Kawano Y, Suzuki K, Yoshitomi K, Kawahara M, Tanaka KI.   +10 more
europepmc   +1 more source

Oxidopamine and oxidative stress: Recent advances in experimental physiology and pharmacology

Chemico-Biological Interactions, 2021
Oxidopamine (6-hydroxydopamine, 6-OHDA) is a toxin commonly used for the creation of experimental animal models of Parkinson's disease, attention-deficit hyperactivity disorder, and Lesch-Nyhan syndrome. Its exact mechanism of action is not completely understood, although there are many indications that it is related to the generation of reactive ...
Igor Pantić, Jelena Cumic, Sanja Radojević Škodrić, Stefan Dugalić, Claude Brodski   +4 more
openalex   +3 more sources

Gray level co-occurrence matrix algorithm as pattern recognition biosensor for oxidopamine-induced changes in lymphocyte chromatin architecture

Journal of Theoretical Biology, 2016
We demonstrate that a proapoptotic chemical agent, oxidopamine, induces dose dependent changes in chromatin textural patterns which can be quantified using the Gray level co-occurrence matrix (GLCM) method. Peripheral blood (heparin-pretreated) samples were treated with oxidopamine (6-OHDA, 6-hydroxydopamine) to achieve effective concentrations of 100,
Igor Pantić, Draga Dimitrijevic, Dejan Nešić, Danica Petrovic   +3 more
openalex   +3 more sources

Unveiling the potency of FDA-approved oxidopamine HBr for cervical cancer regulation and replication proteins

Medical Oncology
Cervical Cancer remains a women's health concern worldwide and ranks among the most prevalent cancers, particularly in developing countries. Many women are diagnosed with cervical cancer, with a substantial number succumbing to the disease even after the availability of vaccines and drugs.
Nawal Helmi, Abdullah Hamadi, Osama M. Al‐Amer, Hassan Madkhali, Atif Abdulwahab A. Oyouni, Amany I. Alqosaibi, Jawaher Almulhim, Rashed Mohammed Alghamdi, Israa J. Hakeem, Misbahuddin M. Rafeeq   +9 more
openalex   +3 more sources