Results 81 to 90 of about 1,328 (132)

AR-negative prostate cancer is vulnerable to loss of JMJD1C demethylase. [PDF]

Proc Natl Acad Sci U S A, 2021
Yoshihama Y, LaBella KA, Kim E, Bertolet L, Colic M, Li J, Shang X, Wu CJ, Spring DJ, Wang YA, Hart T, DePinho RA.   +11 more
europepmc   +1 more source

SIRT6 cooperates with KDM5C to transcriptionally silence MICAL2 and inhibit tumorigenesis in pancreatic cancer. [PDF]

Cell Commun Signal
Leng S, Liu W, Han Y, Dang Z, Zhang F, Yu W.   +5 more
europepmc   +1 more source

The histone demethylase dLsd1 regulates organ size by silencing transposable elements. [PDF]

Commun Biol
Selmi I, Texier M, Aguirrenbegoa M, Merce C, Fraisse-Lepourry L, Mugat B, Mohamed M, Chambeyron S, Cribbs D, Di Stefano L.   +9 more
europepmc   +1 more source

Influence of the TorD signal peptide chaperone on Tat-dependent protein translocation. [PDF]

PLoS One, 2021
Bageshwar UK, DattaGupta A, Musser SM.
europepmc   +1 more source

The duration of induction and species influences the downregulation of cytochrome P450 by the interferon inducer polyinosinic acid-polycytidylic acid

, 1995
Interferon (IFN) has long been recognized to downregulate cytochrome P450-mediated drug metabolism. Some investigations have shown that induced P450 enzymes tend to be more resistant to the depressant effect of IFN, whereas constitutive forms of P450 are

core  

Individuals with reported and novel KDM5C variants present with seizures, a feature recapitulated in a Drosophila model. [PDF]

Hum Mol Genet
Terry BK, Mahoney A, Lee BI, Secombe J.
europepmc   +1 more source

Recreating the natural evolutionary trend in key microdomains provides an effective strategy for engineering of a thermomicrobial N-demethylase. [PDF]

J Biol Chem, 2022
Xin Y, Shen C, Tang M, Guo Z, Shi Y, Gu Z, Shao J, Zhang L.   +7 more
europepmc   +1 more source

An engineered gut bacterium protects against dietary methylmercury exposure in pregnant mice. [PDF]

Cell Host Microbe
Yu KB, Chandra F, Coley-O'Rourke EJ, Paulson ET, Novoselov A, Zhang D, Finnigan D, Paramo J, Lopez-Romero A, Dong TS, Schartup AT, Hsiao EY.   +11 more
europepmc   +1 more source

Physio-pathological effects of m6A modification and its potential contribution to melanoma. [PDF]

Clin Transl Oncol, 2021
Liao Y, Han P, Zhang Y, Ni B.
europepmc   +1 more source

Dispensable genome and segmental duplications drive the genome plasticity in <i>Fusarium solani</i>. [PDF]

Front Fungal Biol
Navasca A, Singh J, Rivera-Varas V, Gill U, Secor G, Baldwin T.   +5 more
europepmc   +1 more source