Results 1 to 10 of about 74,468,422 (128)
From Fragments to Function: Novel Hydrazone Derivatives as Monoamine Oxidase Inhibitors. [PDF]
ChemMedChemTwelve N‐acylhydrazone derivatives (5a–f, 6a–f) were synthesized and characterized. Compounds displayed potent submicromolar inhibition against both MAO‐A and MAO‐B. Compound 6e exhibited the strongest activity (IC50 = 0.073 μM for MAO‐A; 0.064 μM for MAO‐B). Kinetic and docking analyses confirmed reversible, competitive inhibition via FAD interaction.
Sellitepe HE +5 more
europepmc +2 more sources
, 2016 The preorganized, macrobicyclic azaphane (1) exhibits remarkable strong, selective fluoride binding comparable to the most effective bis(tren) cryptands despite binding anions via only three NH groups coupled with three CH hydrogen bond donors. The lower
Christos A. Ilioudis (2706217) +2 more
core +6 more sources
MILLIMETER/SUBMILLIMETER SPECTROSCOPY OF THE METHYLAMINE PHOTODISSOCIATION PRODUCT AMINOMETHYL RADICAL (·CH₂NH₂) [PDF]
, 2023 Methylamine (CH₃NH₂) is the simplest primary amine and a precursor of the simplest amino acid, glycine. Therefore, methylamine is a molecule of particular interest in astrochemistry and prebiotic chemistry.
Liang, Haocheng
core +1 more source
QUANTUM TUNNELING IN INTERSTELLAR ICE BY AMMONIA (NH₃) AND ACETALDEHYDE (CH₃CHO): CHELATION AGENTS TO ASSIST RNA REPLICATION [PDF]
, 2023 Ion transport represents a vital process in all modern lifeforms, but how early cells could have accomplished this without the complex proteins used by modern cells has remained a mystery.
Marks, Joshua H
core +1 more source
Ferroelectricity Driven by Orbital Resonance of Protons in CH$_3$NH$_3$Cl and CH$_3$NH$_3$Br [PDF]
, 2022 The $\beta$ and $\gamma$ phases of methylammonium chloride CH$_3$NH$_3$Cl and methylammonium bromide CH$_3$NH$_3$Br are identified to be ferroelectric $via$ pyroelectric current and dielectric constant measurements.
Ren, Peng +13 more
core +1 more source
, 2022 It is essential to develop novel zero- and two-dimensional hybrid perovskites to facilitate the development of eco-friendly solar cells. In this study, we investigated the structure and dynamics of [NH(3)(CH(2))(5)NH(3)]CuCl(4) via various ...
Park, Sang Hyeon +3 more
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NX∙∙Y Halogen Bonds. Comparison with NH∙∙Y H-bonds and CX∙∙Y Halogen Bonds [PDF]
, 2016 Quantum calculations examine how the NH∙∙Y H-bond compares to the equivalent NX∙∙Y halogen bond, as well as to comparable CH/CX donors. Succinimide and saccharin, and their corresponding halogen-substituted derivatives, are chosen as the prototype NH/NX ...
Scheiner, Steve, Nepal, Binod
core +1 more source
, 1993 The introduction of the cyanomethyleneamino [CH(CN)NH] group, a new type of peptide bond surrogate, under solid phase peptide synthesis conditions has been studied using both Boc and Fmoc strategies. The pseudohexapeptides H-Arg-Pro-Tyrψ[CH(CN)NH]Ile-Leu-
Madsen, Kjeld +15 more
core +1 more source
Magnetic interactions based on proton orbital motion in CH$_3$NH$_3$PbI$_3$ and CH$_3$NH$_3$PbBr$_3$ [PDF]
The microscopic origin of the remarkable optoelectronic properties of one of the most studied contemporary materials remains unclear. Here, we identify the existence of magnetic interactions between intermolecular proton orbitals in CH$_3$NH$_3$PbI$_3 ...
Ren, Peng +7 more
core +1 more source
Solid-Phase Synthesis of Gly-Ψ[CH(CF3)NH]-Peptides [PDF]
, 2021 The solid-phase synthesis of Gly-Ψ[CH(CF3)NH]-peptides is presented. In order to achieve this goal, the synthesis of Gly-Ψ[CH(CF3)NH]-dipeptides having the C-terminus unprotected, the N-terminus protected as Fmoc- or Teoc-, and possibly side chain ...
Sgorbati, Clara +14 more
core +1 more source