Results 61 to 70 of about 893 (117)

PRIMA-1Met suppresses colorectal cancer independent of p53 by targeting MEK [PDF]

, 2016
This work was supported by Grant No. 81201779 (Hua Xiong) from the National Natural Science Youth Foundation; Grant No. 81502118 (Yanmei Zou) from the National Natural Science Youth Foundation; Grant No.
Duan, Qiuhong, Lu, Tao, Potter, Jane A., Qiu, Hong, Taylor, Garry L., Wang, Yihua, Xiong, Hua, Xiong, Huihua, Xu, Guogang, Yang, Qin, Ye, Dawei, Yu, Shiying, Yuan, Xianglin, Zhang, Peng, Zhu, Feng, Zou, Yanmei   +15 more
core   +2 more sources

Triterpenoid Biosynthesis and Engineering in Plants [PDF]

, 2011
Triterpenoid saponins are a diverse group of natural products in plants and are considered defensive compounds against pathogenic microbes and herbivores.
Kazuki eSaito, Kazuki eSaito, Satoru eSawai   +2 more
core   +3 more sources

Identification of key amino acid residues determining product specificity of 2,3-oxidosqualene cyclase in Oryza species [PDF]

, 2018
Triterpene synthases, also known as 2,3-oxidosqualene cyclases (OSCs), synthesize diverse triterpene skeletons that form the basis of an array of functionally divergent steroids and triterpenoids.
Augustin, Banta, Benveniste, Bergelson, Biasini, Bishop, Bloch, Chang, Chappell, Christianson, Hart, Herrera, Huang, Inagaki, Ito, Ito, Kovach, Matsuda, Morris, Moses, Ohyama, Osbourn, Parks, Pettersen, Salmon, Sang, Sun, Tamura, Thimmappa, Thoma, Weng, Wu, Wu, Wu, Wu, Xiong, Xu, Xu, Xue, Yang   +39 more
core   +1 more source

Elucidation and heterologous reconstitution of plant triterpene biosynthetic pathways [PDF]

Triterpenoids are a diverse and important class of natural products found throughout the plant kingdom. Their structural complexity, derived from the cyclization of oxidosqualene, provides a wide range of biological activities, including roles in plant ...
Hakim, Samuel Edward
core   +2 more sources

2,3-Oxidosqualene cyclase protects liver cells from the injury of intermittent hypoxia by regulating lipid metabolism [PDF]

, 2015
Ling Yu, Qiu-yan Song, Rui-hong Dong, Xiao-juan Rao, Yan Wang, Yan-hong Sang, Yu-min Wu, Yue-qiao Zhen   +7 more
core   +3 more sources

Arylpiperidines as a new class of oxidosqualene cyclase inhibitors [PDF]

, 2016
Balliano, Gianni, Ferrante, Terenzio, OLIARO BOSSO, Simonetta   +2 more
core   +1 more source

The Evolutionary History and Modern Diversity of Triterpenoid Cyclases. [PDF]

Mol Biol Evol
McShea HS, Viens RA, Olagunju BO, Giner JL, Welander PV.   +4 more
europepmc   +1 more source

Identification of 2,3-oxidosqualene cyclase gene in <i>Eleutherococcus senticosus</i> and its regulatory mechanism in saponin synthesis. [PDF]

Hortic Res
Cui Y, Ma J, Jiao M, Zhao X, Ding J, Feng C, Liu P, Long Y, Xing Z.   +8 more
europepmc   +1 more source

Metabolic engineering of Phaeodactylum tricornutum for heterologous production of the plant triterpenoid friedelin. [PDF]

Microb Cell Fact
Nguyen K, Choi MS, Seo S, Song J, Jin E.
europepmc   +1 more source

Deciphering the key pathway for triterpenoid biosynthesis in Azadirachta indica A. Juss.: a comprehensive review of omics studies in nature's pharmacy. [PDF]

Front Plant Sci, 2023
Dave N, Iqbal A, Patel M, Kant T, Yadav VK, Sahoo DK, Patel A.   +6 more
europepmc   +1 more source