ABSTRACT Trastuzumab deruxtecan (T‐DXd) is a third‐generation, HER2‐targeting antibody‐drug conjugate that has been shown to significantly prolong overall survival, compared with standard chemotherapy, when used to treat patients who have “HER2‐low” (HER2 immunohistochemistry [IHC] score 1+; or HER2 IHC 2+ plus in situ hybridization‐negative ...
Andrew Redfern +8 more
wiley +1 more source
Cerebral oximetry-guided anaesthesia and postoperative delirium in elderly patients undergoing off-pump coronary artery bypass grafting: a randomized controlled trial. [PDF]
Tian L +7 more
europepmc +1 more source
Test of long-term uterine survival after allogeneic transplantation in rabbits [PDF]
Avison +26 more
core +1 more source
Awake Percutaneous Cervical Cordotomy in Patients With Cancer: A Technical Report
ABSTRACT Background Percutaneous cervical cordotomy (PCC) is a minimally invasive radiofrequency procedure for intractable unilateral cancer pain. Commonly performed under conscious sedation, awake PCC enables real‐time patient feedback, potentially improving targeting precision and expanding eligibility for patients in whom sedation poses risks ...
Adinda P. Pradhana +6 more
wiley +1 more source
Dapsone Toxicity in Relapsing Polychondritis: Methemoglobinemia and Concomitant Hemolytic Anemia. [PDF]
Magalhães JN, Monteiro A.
europepmc +1 more source
This review critically examines clinical studies on both conventional and machine learning (ML)‐integrated diffuse optical spectroscopy and imaging methods for dermatological applications, with a primary focus on the past decade and inclusion of earlier foundational work where appropriate.
Iftak Hussain +7 more
wiley +1 more source
Severe, Non‐apneic Respiratory Dysfunction and Hypoxia following Generalized Convulsive Seizures
Objective Sudden unexpected death in epilepsy (SUDEP) is a devastating consequence of some generalized convulsive seizures (GCS). Recent work has focused on seizure related apnea as a biomarker of SUDEP risk, frequently without characterizing the adequacy of non‐apneic ventilation or identifying other dysfunctional breathing patterns.
Haley E. Pysick +9 more
wiley +1 more source
Intermittent hypoxia and caffeine in infants born preterm: the ICAF Randomized Clinical Trial. [PDF]
Eichenwald E +10 more
europepmc +1 more source
ABSTRACT In heart failure patients, dopamine therapy, particularly at higher doses, may induce seizures due to its impact on cerebral blood flow and exacerbation of underlying hypoxemia and electrolyte imbalances. Close monitoring and cautious use of dopamine, with consideration of alternative inotropic agents like dobutamine, are essential to mitigate
Chuanwei Zhao +4 more
wiley +1 more source
Naphthalene-Induced Methemoglobinemia With Acute Hemolysis in a Child: A Rare Case of Refractory Hypoxia. [PDF]
Mishra R, Gari P, Rai K, Zarrin F.
europepmc +1 more source

