Results 91 to 100 of about 135,136 (259)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Amorphous multimetal based catalyst for oxygen evolution reaction

open access: yesDiscover Materials
The development of efficient, low-cost water splitting electrocatalysts is needed to store energy by generating sustainable hydrogen from low power clean but intermittent energy sources such as solar and wind.
Zishuai Zhang   +3 more
doaj   +1 more source

Electrocatalytic overall water splitting based on (ZnNiCoFeY)xOy high-entropy oxide supported on MoS2

open access: yesSouth African Journal of Chemical Engineering
Hydrogen energy is a sustainable and clean source that can meet global energy demands without adverse environmental impacts. High-entropy oxides (HEOs), multielement (5 or more) oxides with an equiatomic or near-equatomic elemental composition, offer a ...
Sumayya C. Pathan   +11 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Glancing Angle Deposition for Enhanced Oxygen Evolution Reaction

open access: yesSmall Structures
The oxygen evolution reaction (OER) presents a major kinetic challenge in alkaline water electrolysis. Nickel oxide (NiO) is generally accepted as a favorable material due to its abundance and stability, yet it also exhibits limited intrinsic catalytic ...
Parsa Borhani   +5 more
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Current status of developed electrocatalysts for water splitting technologies: from experimental to industrial perspective

open access: yesNano Convergence
The conversion of electricity into hydrogen (H2) gas through electrochemical water splitting using efficient electrocatalysts has been one of the most important future technologies to create vast amounts of clean and renewable energy.
Duy Thanh Tran   +7 more
doaj   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

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