Results 81 to 90 of about 5,846,908 (308)

Electrocatalysts based on metal@carbon core@shell nanocomposites: An overview

Green Energy & Environment, 2018
Developing low-cost, high-performance catalysts is of fundamental significance for electrochemical energy conversion and storage. In recent years, metal@carbon core@shell nanocomposites have emerged as a unique class of functional nanomaterials that show
Yi Peng, Shaowei Chen
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

The current state of transition metal-based electrocatalysts (oxides, alloys, POMs, and MOFs) for oxygen reduction, oxygen evolution, and hydrogen evolution reactions

Frontiers in Energy Research
Climate change is showing its impacts now more than ever. The intense use of fossil fuels and the resulting CO2 emissions are mainly to blame, accentuating the need to develop further the available energy conversion and storage technologies, which are ...
Henrique Araújo, Henrique Araújo, Biljana Šljukić, Sandra Gago, Diogo M. F. Santos   +4 more
doaj   +1 more source

Co doped MoS2 as Bifunctional Electrocatalyst for Hydrogen Evolution and Oxygen Reduction Reactions

International Journal of Electrochemical Science, 2019
Pure MoS2 and MoS2 compounds were doped with Co using a hydrothermal method. XRD results indicate that two of the five diffraction peak results at 9.2° and 18.2° may be attributed to low crystallinity of MoS2. The (002) diffraction peaks for the Co-doped
Congrong Wang, Shun Wang, Jianguo Lv, Yuxuan Ma, Yongqi Wang, Gaoliang Zhou, Mingsheng Chen, Min Zhao, Xiaoshuang Chen, Lei Yang   +9 more
doaj   +1 more source

Application of Oxygen Reduction Reaction, Oxygen Evolution Reaction and Hydrogen Evolution Reaction in Electrochemical Biosensing

International Journal of Electrochemical Science, 2022
Jianlin Zhou, Ping Qin, Weiyin Liu, Yuwei Liu   +3 more
openaire   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Efficient electrocatalysts derived from praseodymium-doped MOFs and MXene for oxygen reduction, hydrogen evolution, and oxygen evolution reactions

Carbon Trends
In response to the urgent need for high-performance non-precious metal electrocatalysts to address the energy crisis and reduce dependence on fossil fuels, we propose a novel approach to develop a highly selective and efficient electrocatalyst derived ...
Mozhgan Hadavand, Mehdi Mehrpooya, Mohammad Reza Ganjali   +2 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Benchmarking Heterogeneous Electrocatalysts for the Oxygen Evolution Reaction

Journal of the American Chemical Society, 2013
Objective evaluation of the activity of electrocatalysts for water oxidation is of fundamental importance for the development of promising energy conversion technologies including integrated solar water-splitting devices, water electrolyzers, and Li-air batteries.
McCrory, Charles C. L., Jung, Suho, Peters, Jonas C., Jaramillo, Thomas F.   +3 more
openaire   +3 more sources