Results 41 to 50 of about 135,026 (259)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Oxygen desorption – Critical step for the oxygen evolution reaction

Current Opinion in Electrochemistry, 2023
The oxygen evolution reaction (OER) has been widely investigated in computational electrocatalysis. Recent studies suggest that the final oxygen desorption step could be rate-limiting, or even inhibiting, for the classical OER mechanism on the benchmark IrO2 electrocatalyst, and a novel reaction mechanism has been proposed circumventing this bottleneck.
Binninger, Tobias, Kowalski, Piotr M., Eikerling, Michael H.   +2 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Oxygen vacancy-mediated high-entropy oxide electrocatalysts for efficient oxygen evolution reaction

Materials Today Catalysis
Transition metal oxides hold great potential for water splitting due to their tunable electronic structures and abundant availability. However, their inherently poor electrical conductivity and limited catalytic activity hinder their practical ...
Ruonan Liu, Yaotian Yan, Liang Dun, Taili Yang, Bin Qin, Peijia Wang, Wei Cai, Shude Liu, Xiaohang Zheng   +8 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Missing-linker metal-organic frameworks for oxygen evolution reaction

Nature Communications, 2019
While water splitting electrocatalysis provides a means to store electrical energy as fuel, the water oxidation catalysts typically show low performances.
Ziqian Xue, Kang Liu, Qinglin Liu, Yinle Li, Manrong Li, Cheng-Yong Su, Naoki Ogiwara, Hirokazu Kobayashi, Hiroshi Kitagawa, Min Liu, Guangqin Li   +10 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Tracking the correlation between spintronic structure and oxygen evolution reaction mechanism of cobalt-ruthenium-based electrocatalyst

Nature Communications
Regulating the spintronic structure of electrocatalysts can improve the oxygen evolution reaction performance efficiently. Nonetheless, the effects of tuning the spintronic structure for the oxygen evolution reaction mechanisms have rarely been discussed.
Chen Wang, Chaoyuan Deng, Panlong Zhai, Xiaoran Shi, Wei Liu, Dingfeng Jin, Bing Shang, Junfeng Gao, Licheng Sun, Jungang Hou   +9 more
doaj   +1 more source

Al–Pt compounds catalyzing the oxygen evolution reaction

Dalton Transactions, 2023
Al–Pt compounds have been systematically studied under conditions of the oxygen evolution reaction (OER).
Ana María Barrios Jiménez, Olga Sichevych, Ioannis Spanos, Simone G. Altendorf, Alim Ormeci, Iryna Antonyshyn   +5 more
openaire   +5 more sources