Results 71 to 80 of about 135,026 (259)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Electric-field-assisted proton coupling enhanced oxygen evolution reaction

Nature Communications
The discovery of Mn-Ca complex in photosystem II stimulates research of manganese-based catalysts for oxygen evolution reaction (OER). However, conventional chemical strategies face challenges in regulating the four electron-proton processes of OER ...
Xuelei Pan, Mengyu Yan, Qian Liu, Xunbiao Zhou, Xiaobin Liao, Congli Sun, Jiexin Zhu, Callum McAleese, Pierre Couture, Matthew K. Sharpe, Richard Smith, Nianhua Peng, Jonathan England, Shik Chi Edman Tsang, Yunlong Zhao, Liqiang Mai   +15 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

The (In)Stability of Heterostructures During the Oxygen Evolution Reaction

Advanced Energy Materials
AbstractThe urgent need for efficient oxygen evolution reaction (OER) catalysts has led to the development and publication of many heterostructured catalysts. The application of such catalysts with multiple phases tremendously increases the material design dimensions, and numerous interface‐related effects can tune the OER performance.
Indranil Mondal, J. Niklas Hausmann, Stefan Mebs, Shweta Kalra, Gonela Vijaykumar, Konstantin Laun, Ingo Zebger, Sören Selve, Holger Dau, Matthias Driess, Prashanth W Menezes   +10 more
openaire   +2 more sources

Benchmarking Heterogeneous Electrocatalysts for the Oxygen Evolution Reaction

Journal of the American Chemical Society, 2013
Objective evaluation of the activity of electrocatalysts for water oxidation is of fundamental importance for the development of promising energy conversion technologies including integrated solar water-splitting devices, water electrolyzers, and Li-air batteries.
McCrory, Charles C. L., Jung, Suho, Peters, Jonas C., Jaramillo, Thomas F.   +3 more
openaire   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

The current state of transition metal-based electrocatalysts (oxides, alloys, POMs, and MOFs) for oxygen reduction, oxygen evolution, and hydrogen evolution reactions

Frontiers in Energy Research
Climate change is showing its impacts now more than ever. The intense use of fossil fuels and the resulting CO2 emissions are mainly to blame, accentuating the need to develop further the available energy conversion and storage technologies, which are ...
Henrique Araújo, Henrique Araújo, Biljana Šljukić, Sandra Gago, Diogo M. F. Santos   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Efficient electrocatalysts derived from praseodymium-doped MOFs and MXene for oxygen reduction, hydrogen evolution, and oxygen evolution reactions

Carbon Trends
In response to the urgent need for high-performance non-precious metal electrocatalysts to address the energy crisis and reduce dependence on fossil fuels, we propose a novel approach to develop a highly selective and efficient electrocatalyst derived ...
Mozhgan Hadavand, Mehdi Mehrpooya, Mohammad Reza Ganjali   +2 more
doaj   +1 more source

Application of Oxygen Reduction Reaction, Oxygen Evolution Reaction and Hydrogen Evolution Reaction in Electrochemical Biosensing

International Journal of Electrochemical Science, 2022
Jianlin Zhou, Ping Qin, Weiyin Liu, Yuwei Liu   +3 more
openaire   +1 more source