Results 241 to 250 of about 57,040 (314)

Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post   +4 more
wiley   +1 more source

The wider perspective: Barriers and recommendations for transfusion support for patients with sickle cell disease in low‐ and middle‐income countries

open access: yesBritish Journal of Haematology, EarlyView.
Globally, sickle cell disease (SCD) is the most common inherited haemoglobinopathy. The highest burden of SCD is encountered in low‐ and middle‐income countries (LMICs), most of which lack the resources to contend with the disease. Blood transfusion remains central to the emergent treatment and prevention of complications of SCD.
Jeremy W. Jacobs   +13 more
wiley   +1 more source

Hydrogen gas inhalation ameliorates glomerular enlargement after hypoxic-ischemic insult in asphyxiated piglet model. [PDF]

open access: yesSci Rep
Iwaki T   +16 more
europepmc   +1 more source

Burns, Aging, and Appalachia: The Untold Story of Hospital Stays. [PDF]

open access: yesCureus
Rahimpour A   +7 more
europepmc   +1 more source

Systemic EP4 receptor agonist and Arginase‐1 therapy in a murine model of chronic asthma and influenza virus‐induced asthma exacerbation

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Myeloid‐derived suppressor cells (MDSCs) play important roles in the pathogenesis of asthma. Recent studies demonstrate that their function can be modulated by different pharmacological approaches. In this study, we focussed on the effects of systemically administered prostaglandin EP4 receptor agonist L‐902,688 and pegylated ...
Tim Lange   +7 more
wiley   +1 more source

Impact of Vitamin C on Immune Response and Edema Following Near‐Infrared Photoimmunotherapy (NIR‐PIT)

open access: yesCancer Science, EarlyView.
Acute temporal edema, which can potentially obstruct the airway, is the most common adverse effect associated with near‐infrared photoimmunotherapy (NIR‐PIT) of head and neck cancer. Leveraging the chemical mechanisms of NIR‐PIT, vitamin C has been shown to suppress such edema and enhance cytotoxicity by quenching reactive oxygen species and donating ...
Hiroshi Yamamoto   +10 more
wiley   +1 more source

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