Results 51 to 60 of about 5,141,564 (262)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Reaproveitamento de óxidos de manganês de pilhas descartadas para eletrocatálise da reação de redução de oxigênio em meio básico Use of manganese oxides recovered from spent batteries in electrocatalysis of oxygen reduction reaction in alkaline medium

open access: yesQuímica Nova, 2010
The oxygen reduction reaction was studied in alkaline media using manganese oxides obtained from spent batteries as electrocatalysts. Three processes were used to recover manganese oxides from spent batteries.
Daniel C. Rascio   +5 more
doaj   +1 more source

Oxygen reduction on single crystal platinum electrodes in phosphoric acid solutions [PDF]

open access: yesJournal of the Serbian Chemical Society, 1999
Oxygen reduction reaction has been studied on Pt low index planes in 0.1Mand 85% H3PO4 using hanging meniscus rotating disc electrode technique.
Tanaka A., Adžić R., Nikolić B.
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Spatial oxygen heterogeneity in a Hediste diversicolor irrigated burrow [PDF]

open access: yes, 2011
The heterogeneity of oxygen distribution in a Hediste diversicolor burrow environment was investigated in a laboratory experiment using a 6-mm thick tank equipped with oxygen planar optodes. The twodimensional oxygen distribution in a complete burrow was
Franck Gilbert   +11 more
core   +1 more source

Investigation of the Effect of Hydrophilicity on Oxygen Reduction Reaction Property with Measurement of Water Vapor Specific Surface Area

open access: yesElectrochemistry, 2021
For oxygen reduction reaction of an air battery which uses oxygen and water as reactants, it is important to control not only gas diffusivity but also hydrophilicity. In this study, the effect of hydrophilicity was investigated quantitatively.
Satoko TAKASE   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Three Toxic Gases Meet in the Mitochondria

open access: yesFrontiers in Physiology, 2015
The rationale of the study was two-fold : (i) develop a functional synthetic model of the Cytochrome c oxidase (CcO) active site, (ii) use it as a convenient tool to understand or predict the outcome of the reaction of CcO with ligands (physiologically ...
Richard A Decreau   +2 more
doaj   +1 more source

Synthesis and Electrochemical Study of Three-Dimensional Graphene-Based Nanomaterials for Energy Applications

open access: yesNanomaterials, 2020
Graphene is an attractive soft material for various applications due to its unique and exclusive properties. The processing and preservation of 2D graphene at large scales is challenging due to its inherent propensity for layer restacking.
Antony R. Thiruppathi   +4 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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