Results 11 to 20 of about 583,939 (258)

Intracellular oxygen tension limits muscle contraction-induced change in muscle oxygen consumption under hypoxic conditions during Hb-free perfusion. [PDF]

, 2017
Under acute hypoxic conditions, the muscle oxygen uptake (mV˙O2) during exercise is reduced by the restriction in oxygen-supplied volume to the mitochondria within the peripheral tissue. This suggests the existence of a factor restricting the mV˙O2 under
Furuichi, Yasuro, Hashimoto, Takeshi, Iwase, Satoshi, Jue, Thomas, Masuda, Kazumi, Ojino, Minoru, Takakura, Hisashi, Yamada, Tatsuya   +7 more
core   +1 more source

Oxygen Saturation and Outcomes in Preterm Infants [PDF]

New England Journal of Medicine, 2013
The clinically appropriate range for oxygen saturation in preterm infants is unknown. Previous studies have shown that infants had reduced rates of retinopathy of prematurity when lower targets of oxygen saturation were used.In three international randomized, controlled trials, we evaluated the effects of targeting an oxygen saturation of 85 to 89%, as
Group, Boost II United Kingdom Collaborative, Group, Boost II Australia Collaborative, Group, Boost II New Zealand Collaborative, Stenson, B, Tarnow-Mordi, W, Darlow, B, Simes, J, Juszczak, E, Askie, L, Battin, M, Bowler, U, Broadbent, R, Cairns, P, Davis, P, Deshpande, S, Donoghoe, M, Doyle, L, Fleck, B, Ghadge, A, Hague, W, Halliday, H, Hewson, M, King, A, Kirby, A, Marlow, N, Meyer, M, Morley, C, Simmer, K, Tin, W, Wardle, S, Brocklehurst, P   +30 more
openaire   +5 more sources

Oxygen saturation in cystic fibrosis. [PDF]

Archives of Disease in Childhood, 1991
The availability of non-invasive oxygen saturation (SaO2) measurement could prove to be a useful tool for following up the progress of patients with cystic fibrosis. The present study was undertaken to compare its use with other routine measurements in the clinic.
R Dinwiddie, M Betancourt, G Slade
openaire   +3 more sources

The use of pulse oximetry in evaluation of pulp vitality in immature permanent teeth [PDF]

, 2016
Background and aim: The current methods of pulp vitality assessment, either electric or thermal, are of limited use in children. Recently, traumatized and immature teeth may not respond to such methods and because such methods require subjective ...
Ahmadi, M., Ashari, M.A., Bargrizan, M., Ramezani, J.   +3 more
core  

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, Volume 19, Issue 6, Page 1687-1706, June 2025.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

In vivo multi-parametric imaging of metastatic and non-metastatic breast cancer [PDF]

, 2017
A current issue in cancer therapy is the characterization of metastatic tumors, which can increase ease of treatment and patient trials. We present an in vivo study of metastatic (4T1) and non-metastatic (4T1-TWIST KO) breast tumor sister cell lines to ...
Rasul, Raisa B
core   +2 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Instantaneous venous oxygenation estimation using the Photoplethysmograph (PPG) waveform [PDF]

, 2011
In this study oesophageal photoplethysmograph data from eight patients under positive pressure ventilation were analysed in order to test the hypothesis that the modulations created by the ventilation in the AC Photoplethysmograph (PPG) signal could be ...
Cohen L, Echiadis A S, K Shafqat, Kyriacou P A, P A Kyriacou, R M Langford, Richman M, S K Pal, Shelley K H, Welch J   +9 more
core   +1 more source

Pulse Oximeter Oxygen Saturation in Prediction of Arterial Oxygen Saturation in Liver Transplant Candidates [PDF]

Hepatitis Monthly, 2014
Liver transplant is the only definitive treatment for many patients with end stage liver disease. Presence and severity of preoperative pulmonary disease directly affect the rate of postoperative complications of the liver transplantation. Arterial blood gas (ABG) measurement, performed in many transplant centers, is considered as a traditional method ...
Seiyed Mohammad Ali Ghayumi, Abolfazl Khalafi-Nezhad, Zahra Jowkar   +2 more
openaire   +2 more sources

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source