Results 321 to 330 of about 242,366 (388)

SOX6 enhances vascular smooth muscle cell phenotypic switching and elevates blood pressure by activating autophagy

Animal Models and Experimental Medicine, EarlyView.
Sox6 expression is elevated in hypertensive conditions and promotes vascular smooth muscle cell phenotypic switching through autophagy activation. Using gain‐ and loss‐of‐function approaches both in vitro and in vivo, we demonstrate that Sox6 regulates blood pressure and vascular remodeling, highlighting its potential as a novel therapeutic target for ...
Qianhui Ling, Xilan Dong, Liyan Mao, Chengjun Huang, Linjing Cong, Haizeng Zhang, Jun Cai, Zhenzhen Chen   +7 more
wiley   +1 more source

ECMO Support in Pediatric Populations with the Newborn ECMOLife Centrifugal Pump. [PDF]

Medicina (Kaunas)
Pace Napoleone C, Condello I, Cascarano MT, Aidala E, Peruzzi L, Molinari I, Rivoldini C, Di Carlo MS, Iannandrea S, Bonaveglio E.   +9 more
europepmc   +1 more source

Advances on Albumin‐Based Carriers for Anticancer Drug Delivery

Advanced NanoBiomed Research, EarlyView.
This study systematically classifies the drug delivery modes of albumin by examining the characteristics of its surface‐active groups and internal binding sites. It provides an in‐depth analysis of various drug delivery strategies and their corresponding targeting mechanisms.
Ruoli Zhou, Rongbin Zhong, Zhonghui Luo, Hua Wei, Cui‐Yun Yu   +4 more
wiley   +1 more source

Effect of mild hypothermia vs normothermia cardiopulmonary bypass on postoperative bleeding in patients undergoing coronary artery bypass grafting: protocol of a multi-center, randomized, controlled trial. [PDF]

BMC Surg
Wang J, Wang T, Zhang H, Zhang Q, Liu G, Yan S, Wang Q, Teng Y, Wang J, Hu Q, Ji B.   +10 more
europepmc   +1 more source

Engineered Hydrogels Revolutionize Locoregional Cancer Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review systematically summarizes the latest research progress on injectable hydrogels in cancer immunotherapy, highlighting their unique advantages in precise immune activation, local drug‐controlled release, and immune microenvironment remodeling. These features provide innovative solutions to overcome the bottlenecks of systemic side effects and
Jiyong Wei, Chunliu Huang, Zenghua Zhou, Yanni Lan   +3 more
wiley   +1 more source

A safety comparison of heparin and argatroban anticoagulation in veno-venous extracorporeal membrane oxygenation with a focus on bleeding. [PDF]

Transfus Med
Burša F, Máca J, Sagan J, Sklienka P, Němcová S, Kučerová Z, Romanová T, Jor O, Kondé A, Janošek J, Frelich M.   +10 more
europepmc   +1 more source

Impact of Extracorporeal Membrane Oxygenation Circuitry on Remdesivir. [PDF]

J Pediatr Pharmacol Ther
Cies JJ, Moore WS, Deacon J, Enache A, Chopra A.   +4 more
europepmc   +1 more source

Activated Partial Thromboplastin Time and Anti-IIa Monitoring in Argatroban Anticoagulation in COVID-19 Patients on Venovenous Extracorporeal Membrane Oxygenation. [PDF]

Clin Appl Thromb Hemost
Burša F, Frelich M, Sklienka P, Němcová S, Kučerová Z, Jor O, Romanová T, Kondé A, Janošek J, Sagan J, Máca J.   +10 more
europepmc   +1 more source