Results 41 to 50 of about 58,257 (152)

An Attempt to Establish the Consensus Regarding the Diagnosis, Classification, and Treatment of Rosacea in Japan Using a Modified Delphi Method: The Japan Rosacea Consensus

open access: yesThe Journal of Dermatology, Volume 53, Issue 4, Page 605-618, April 2026.
ABSTRACT In Japan, rosacea has attracted increasing interest. However, because rosacea had been thought to be relatively rare in Japan, the perception of this disease varies among dermatologists. To address these challenges, this study developed a consensus regarding the diagnosis, classification, and treatment of rosacea using a modified Delphi method
Kenshi Yamasaki   +9 more
wiley   +1 more source

A new nasal decongestant, A-57219: a comparison with oxymetazoline

open access: yes, 1987
2-(4-Amino-3,5-dichlorobenzyl)imidazolin hydrochloride (A-57219), has α1-agonist/α2-antagonist activity and was more effective and long-acting than oxymetazoline on canine nasal mucosa, in-vitro and in-vivo.
John F DeBernardis   +5 more
core   +1 more source

The effects of topical oxymetazoline on eyelid position, eye redness, and patient-reported eye appearance: A randomized controlled trial

open access: yes, 2023
This study assesses the effects of topical oxymetazoline 0.1% on eyelid position, eye redness, and patient-perceived eye appearance in patients without severe ptosis.
Marissa K. Shoji   +13 more
core   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +206 more
wiley   +1 more source

Development and optimization of a novel sustained-release dextran tablet formulation for propranolol hydrochloride [PDF]

open access: yes, 2006
A novel oral controlled delivery system for propranolol hydrochloride (PPL) was developed and optimized. The in vitro dissolution profiles of sustained-release matrix tablets of racemic PPL were determined and compared with the United States Pharmacopeia
Pedraz, José Luis   +5 more
core   +1 more source

Analgesic Effect of Cocaine and Lidocaine/Xylometazoline in Healthy Volunteers Undergoing Awake Nasal Intubation: A Randomized Controlled Crossover Trial

open access: yesActa Anaesthesiologica Scandinavica, Volume 69, Issue 6, July 2025.
ABSTRACT Background Several drugs may be used to minimize pain during nasal intubation in awake patients. We hypothesized that the analgesic effect of cocaine would be at least as good (non‐inferior) as that of lidocaine with xylometazoline rated as maximum pain felt during awake nasal intubation of healthy volunteers.
Mo Haslund Larsen   +8 more
wiley   +1 more source

Ferulic Acid in the Treatment of Papulopustular Rosacea: A Randomized Controlled Study

open access: yesJournal of Cosmetic Dermatology, Volume 24, Issue 1, January 2025.
ABSTRACT Background Rosacea is a chronic inflammatory skin disease characterized by flushing, erythema, papules, and pustules on the central face. It affects patient appearance and is noted for its chronicity, recurrence, and resistance to treatment. Effective rosacea treatment requires repairing the skin barrier, reducing inflammation, and promoting ...
Xing Wang   +9 more
wiley   +1 more source

Cocaine versus xylometazoline to prevent epistaxis after nasotracheal intubation: A randomized trial

open access: yesActa Anaesthesiologica Scandinavica, Volume 68, Issue 9, Page 1192-1199, October 2024.
Abstract Background Nasotracheal intubation is associated with a risk of epistaxis. Several drugs, including cocaine and xylometazoline may be used as decongestants prior to nasotracheal intubation to prevent this. We hypothesized that xylometazoline would prevent epistaxis more effectively than cocaine, demonstrated by a lower proportion of patients ...
Mo H. Larsen   +5 more
wiley   +1 more source

Cost‐Effectiveness of Topical Prophylaxis Against Tympanostomy Tube Otorrhea: An Economic Decision Analysis

open access: yesOTO Open, Volume 8, Issue 3, July–September 2024.
Abstract Objective To evaluate the cost‐effectiveness of various topical prophylaxis strategies against posttympanostomy otorrhea using a break‐even analysis. Study Design An economic decision analysis of data collected from purchasing records and the literature. Setting An academic center.
Grant Conner   +3 more
wiley   +1 more source

Hemodynamic and pharmacokinetic analysis of oxymetazoline use during nasal surgery in children

open access: yes, 2019
OBJECTIVES/HYPOTHESIS:Oxymetazoline is an α-adrenergic agonist that is commonly used as a topical hemostatic agent in the operating room during ear, nose, and throat surgery.
Joseph D. Tobias   +11 more
core   +1 more source
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